High speed phase distortion measurement and compensation for focusing in space and time

Reto Fiolka; Meng Cui

doi:10.1117/12.2001121

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22 February 2013 High speed phase distortion measurement and compensation for focusing in space and time

Reto Fiolka, Meng Cui

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Proceedings Volume 8589, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XX; 85890V (2013) https://doi.org/10.1117/12.2001121
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Random scattering and aberrations severely limit the imaging depth in optical microscopy. We introduce a rapid, parallel wavefront compensation technique that efficiently compensates even highly complex phase distortions. Using coherence gated backscattered light as a feedback signal, we focus light deep inside highly scattering brain tissue. We demonstrate that the same wavefront optimization technique can also be used to compensate spectral phase distortions in ultrashort laser pulses using nonlinear iterative feedback. We can restore transform limited pulse durations at any selected target location and compensate for dispersion that has occurred in the optical train and within the sample.

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Reto Fiolka and Meng Cui "High speed phase distortion measurement and compensation for focusing in space and time ", Proc. SPIE 8589, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XX, 85890V (22 February 2013); https://doi.org/10.1117/12.2001121

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