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21 February 2013Diffuse reflectance spectroscopy: a clinical study of tuberculin skin tests reading
Diffuse reflectance spectroscopy is a technique widely used to determine optical properties of tissues: scattering and
absorption coefficients. In this study, we present the development of a low-cost optical instrument usable in a clinical
environment based upon the spatially resolved diffuse reflectance spectroscopy approach. This instrument has been used in a clinical study to support the diagnosis of tuberculosis. The idea is to establish a new scanning method for an early detection of inflammation due to a reagent injection, before the onset of visual signs. Results comparing the instrumental and classical clinical readings are presented.
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Anne Koenig, Sophie Grande, Karima Dahel, Anne Planat-Chrétien, Vincent Poher, Catherine Goujon, Jean-Marc Dinten, "Diffuse reflectance spectroscopy: a clinical study of tuberculin skin tests reading," Proc. SPIE 8592, Biomedical Applications of Light Scattering VII, 85920S (21 February 2013); https://doi.org/10.1117/12.2002314