Changes in strain and blood flow in the outflow tract of chicken embryo hearts observed with spectral domain optical coherence tomography after outflow tract banding

Zhenhe Ma; Linlin Du; Qiaoyun Wang; Zhongdi Chu; Xuan Zang; Fengwen Wang; Ruikang K. Wang

doi:10.1117/12.2002999

26 March 2013 Changes in strain and blood flow in the outflow tract of chicken embryo hearts observed with spectral domain optical coherence tomography after outflow tract banding

Zhenhe Ma, Linlin Du, Qiaoyun Wang, Zhongdi Chu, Xuan Zang, Fengwen Wang, Ruikang K. Wang

Author Affiliations +

Proceedings Volume 8593, Optical Methods in Developmental Biology; 859305 (2013) https://doi.org/10.1117/12.2002999
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

In this paper, we demonstrated the use of a spectral domain optical coherence tomography (OCT) in visualizing and quantifying changes in cardiac wall strain and blood-flow velocities under normal and altered hemodynamic conditions in chicken embryos at an early stage of development, focusing on the heart outflow tract (OFT). OCT imaging allowed in vivo evaluation strain and strain rate of the myocardium of the OFT through analyzing the periodic variation of the myocardial wall thickness. We found that alterations in hemodynamic conditions, through OFT banding, Changed strain and blood-flow velocities through the OFT as expected.

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Zhenhe Ma, Linlin Du, Qiaoyun Wang, Zhongdi Chu, Xuan Zang, Fengwen Wang, and Ruikang K. Wang "Changes in strain and blood flow in the outflow tract of chicken embryo hearts observed with spectral domain optical coherence tomography after outflow tract banding", Proc. SPIE 8593, Optical Methods in Developmental Biology, 859305 (26 March 2013); https://doi.org/10.1117/12.2002999

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