Development of a 3D ultrasound system to investigate post-hemorrhagic hydrocephalus in pre-term neonates

J. Kishimoto; D. Lee; K. St. Lawrence; W. Romano; A. Fenster; S. de Ribaupierre

doi:10.1117/12.2006646

29 March 2013 Development of a 3D ultrasound system to investigate post-hemorrhagic hydrocephalus in pre-term neonates

J. Kishimoto, D. Lee, K. St. Lawrence, W. Romano, A. Fenster, S. de Ribaupierre

Proceedings Volume 8675, Medical Imaging 2013: Ultrasonic Imaging, Tomography, and Therapy; 86751M (2013) https://doi.org/10.1117/12.2006646
Event: SPIE Medical Imaging, 2013, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

Clinical intracranial ultrasound (US) is performed as a standard of care on neonates at risk of intraventricular hemorrhaging (IVH) and is also used after a diagnosis to monitor for potential ventricular dilation. However, it is difficult to estimate the volume of ventricles with 2D US due to their irregular shape. We developed a 3D US system to be used as an adjunct to a clinical system to investigate volumetric changes in the ventricles of neonates with IVH. Our system has been found have an error of within 1% of actual distance measurements in all three directions and volume measurements of manually segmented volumes from phantoms were not statistically significantly different from the actual values (p>0.3). Interobserver volume measurements of the lateral ventricles in a patient with grade III IVH found no significant differences between measurements. There is the potential to use this system in IVH patients to monitor the progression of ventriculomegaly over time.

Citation Download Citation

J. Kishimoto, D. Lee, K. St. Lawrence, W. Romano, A. Fenster, and S. de Ribaupierre "Development of a 3D ultrasound system to investigate post-hemorrhagic hydrocephalus in pre-term neonates", Proc. SPIE 8675, Medical Imaging 2013: Ultrasonic Imaging, Tomography, and Therapy, 86751M (29 March 2013); https://doi.org/10.1117/12.2006646

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