Detecting breast microcalcifications using super-resolution ultrasound imaging: a clinical study

Lianjie Huang; Yassin Labyed; Kenneth Hanson; Daniel Sandoval; Jennifer Pohl; Michael Williamson

doi:10.1117/12.2007653

29 March 2013 Detecting breast microcalcifications using super-resolution ultrasound imaging: a clinical study

Lianjie Huang, Yassin Labyed, Kenneth Hanson, Daniel Sandoval, Jennifer Pohl, Michael Williamson

Author Affiliations +

Proceedings Volume 8675, Medical Imaging 2013: Ultrasonic Imaging, Tomography, and Therapy; 86751O (2013) https://doi.org/10.1117/12.2007653
Event: SPIE Medical Imaging, 2013, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

Imaging breast microcalcifications is crucial for early detection and diagnosis of breast cancer. It is challenging for current clinical ultrasound to image breast microcalcifications. However, new imaging techniques using data acquired with a synthetic-aperture ultrasound system have the potential to significantly improve ultrasound imaging. We recently developed a super-resolution ultrasound imaging method termed the phase-coherent multiple-signal classification (PC-MUSIC). This signal subspace method accounts for the phase response of transducer elements to improve image resolution. In this paper, we investigate the clinical feasibility of our super-resolution ultrasound imaging method for detecting breast microcalcifications. We use our custom-built, real-time synthetic-aperture ultrasound system to acquire breast ultrasound data for 40 patients whose mammograms show the presence of breast microcalcifications. We apply our super-resolution ultrasound imaging method to the patient data, and produce clear images of breast calcifications. Our super-resolution ultrasound PC-MUSIC imaging with synthetic-aperture ultrasound data can provide a new imaging modality for detecting breast microcalcifications in clinic without using ionizing radiation.

Citation Download Citation

Lianjie Huang, Yassin Labyed, Kenneth Hanson, Daniel Sandoval, Jennifer Pohl, and Michael Williamson "Detecting breast microcalcifications using super-resolution ultrasound imaging: a clinical study", Proc. SPIE 8675, Medical Imaging 2013: Ultrasonic Imaging, Tomography, and Therapy, 86751O (29 March 2013); https://doi.org/10.1117/12.2007653

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