Recognition as a challenging label-free optical sensing system

Günter Gauglitz

doi:10.1117/12.2021797

3 May 2013 Recognition as a challenging label-free optical sensing system

Günter Gauglitz

Proceedings Volume 8774, Optical Sensors 2013; 87740I (2013) https://doi.org/10.1117/12.2021797
Event: SPIE Optics + Optoelectronics, 2013, Prague, Czech Republic

Abstract

Optical biosensors are increasingly used in application areas of environmental analysis, healthcare and food safety. The quality of the biosensor’s results depends on the interaction layer, the detection principles, and evaluation strategies, not only on the biopolymer layer but also especially on recognition elements. Using label-free optical sensing, non-specific interaction between sample and transducer has to be reduced, and the selectivity of recognition elements has to be improved. For this reason, strategies to avoid non-specific interaction even in blood and milk are discussed, a variety of upcoming recognition is given. Based on the classification of direct optical detection methods, some examples for the above mentioned applications are reviewed. Trends as well as advantages of parallel multisport detection for kinetic evaluation are also part of the lecture.

Citation Download Citation

Günter Gauglitz "Recognition as a challenging label-free optical sensing system", Proc. SPIE 8774, Optical Sensors 2013, 87740I (3 May 2013); https://doi.org/10.1117/12.2021797

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