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18 June 2013 Near-infrared hyperspectral imaging of atherosclerotic tissue phantom
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A method to identify vulnerable plaques that are likely to cause acute coronary events has been required. The object of this study is identifying vulnerable plaques by hyperspectral imaging in near-infrared range (NIR-HSI) for an angioscopic application. In this study, NIR-HSI of atherosclerotic tissue phantoms was demonstrated under simulated angioscopic conditions. NIR-HSI system was constructed by a NIR super continuum light and a mercury-cadmium-telluride camera. Spectral absorbance values were obtained in the wavelength range from 1150 to 2400 nm at 10 nm intervals. The hyperspectral images were constructed with spectral angle mapper algorithm. As a result, detections of the lipid area in the atherosclerotic tissue phantom under angioscopic observation conditions were achieved especially in the wavelength around 1200 nm, which corresponds to the second overtone of CH stretching vibration mode.
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K. Ishii, R. Nagao, A. Kitayabu, and K. Awazu "Near-infrared hyperspectral imaging of atherosclerotic tissue phantom", Proc. SPIE 8798, Clinical and Biomedical Spectroscopy and Imaging III, 87980Z (18 June 2013);

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