Hydroxyapatite thin films synthesized by Pulsed Laser Deposition onto titanium mesh implants for cranioplasty applications

L. Duta; G. E. Stan; A. C. Popescu; G. Socol; F. M. Miroiu; I. N. Mihailescu; A. Ianculescu; I. Poeata; A. Chiriac

doi:10.1117/12.2032338

10 June 2013 Hydroxyapatite thin films synthesized by Pulsed Laser Deposition onto titanium mesh implants for cranioplasty applications

L. Duta, G. E. Stan, A. C. Popescu, G. Socol, F. M. Miroiu, I. N. Mihailescu, A. Ianculescu, I. Poeata, A. Chiriac

Author Affiliations +

Proceedings Volume 8882, ROMOPTO 2012: Tenth Conference on Optics: Micro- to Nanophotonics III; 888208 (2013) https://doi.org/10.1117/12.2032338
Event: ROMOPTO International Conference on Micro- to Nano-Photonics III, 2012, Bucharest, Romania

Abstract

We report on the synthesis of advanced nanostructured hydroxyapatite thin films onto 3D titanium (Ti) mesh substrates by Pulsed Laser Deposition method. Morphological and structural investigations as well as pull-out tests proved the stoichiometric transfer of crystalline hydroxyapatite (HA) films along with their good adherence. In vivo tests were performed on 12 patients (six with simple Ti mesh, six with Ti mesh biofunctionalized with HA). The tomodensitometry analysis of the cranial control scans evidenced the process of osseogenesis. For four patients with implanted HA/Ti mesh structures, the modification of the value obtained on Hounsfield scale was observed at the level of implant, proving the progress of osseointegration. We conclude that the structures exhibit excellent bonding strength and functionality, and are suitable for neurosurgical applications.

Citation Download Citation

L. Duta, G. E. Stan, A. C. Popescu, G. Socol, F. M. Miroiu, I. N. Mihailescu, A. Ianculescu, I. Poeata, and A. Chiriac "Hydroxyapatite thin films synthesized by Pulsed Laser Deposition onto titanium mesh implants for cranioplasty applications", Proc. SPIE 8882, ROMOPTO 2012: Tenth Conference on Optics: Micro- to Nanophotonics III, 888208 (10 June 2013); https://doi.org/10.1117/12.2032338

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available