Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat

Claus-Peter Richter; Suhrud M. Rajguru; Alan Robinson; Hunter K. Young

doi:10.1117/12.2049322

20 March 2014 Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat

Claus-Peter Richter, Suhrud M. Rajguru, Alan Robinson, Hunter K. Young

Proceedings Volume 8928, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics; 892818 (2014) https://doi.org/10.1117/12.2049322
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Infrared neural stimulation (INS) has been used in the past to evoke neural activity from hearing and partially deaf animals. All the responses were excitatory. In Aplysia californica, Duke and coworkers demonstrated that INS also inhibits neural responses [1], which similar observations were made in the vestibular system [2, 3]. In deaf white cats that have cochleae with largely reduced spiral ganglion neuron counts and a significant degeneration of the organ of Corti, no cochlear compound action potentials could be observed during INS alone. However, the combined electrical and optical stimulation demonstrated inhibitory responses during irradiation with infrared light.

Citation Download Citation

Claus-Peter Richter, Suhrud M. Rajguru, Alan Robinson, and Hunter K. Young "Infrared neural stimulation (INS) inhibits electrically evoked neural responses in the deaf white cat", Proc. SPIE 8928, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics, 892818 (20 March 2014); https://doi.org/10.1117/12.2049322

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