Focusing light in scattering media by ultrasonically encoded wavefront shaping (SEWS)

Jian Wei Tay; Puxiang Lai; Yuta Suzuki; Lihong V. Wang

doi:10.1117/12.2037037

3 March 2014 Focusing light in scattering media by ultrasonically encoded wavefront shaping (SEWS)

Jian Wei Tay, Puxiang Lai, Yuta Suzuki, Lihong V. Wang

Proceedings Volume 8943, Photons Plus Ultrasound: Imaging and Sensing 2014; 89434P (2014) https://doi.org/10.1117/12.2037037
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

Wavefront distortion in scattering media can be compensated for using optical wavefront shaping. In this technique, a spatial light modulator (SLM) is used to apply a spatially distributed phase shift to the optical field. A genetic optimization algorithm was used to obtain the SLM pattern which best focuses light within the medium. The target volume is defined by using a focused ultrasound beam to encode light travelling within the acoustic focus. The ultrasonically-encoded light is measured and used as feedback to the algorithm, which then searches for the pattern which maximizes the encoded light intensity. We call this technique ultrasonically-encoded wavefront shaping (SEWS). Using SEWS, we focused light into a scattering medium consisting of ground glass diffuser and a gelatin phantom. The optical intensity at the target was increased by 11 times over the original intensity. These results were validated using fluorescent imaging at the ultrasonic focus.

Citation Download Citation

Jian Wei Tay, Puxiang Lai, Yuta Suzuki, and Lihong V. Wang "Focusing light in scattering media by ultrasonically encoded wavefront shaping (SEWS)", Proc. SPIE 8943, Photons Plus Ultrasound: Imaging and Sensing 2014, 89434P (3 March 2014); https://doi.org/10.1117/12.2037037

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