Iron oxide nanoparticles in different modifications for antimicrobial phototherapy

Elena S. Tuchina; Kristina V. Kozina; Nikita A. Shelest; Vyacheslav I. Kochubey; Valery V. Tuchin

doi:10.1117/12.2038421

24 March 2014 Iron oxide nanoparticles in different modifications for antimicrobial phototherapy

Elena S. Tuchina, Kristina V. Kozina, Nikita A. Shelest, Vyacheslav I. Kochubey, Valery V. Tuchin

Proceedings Volume 8955, Colloidal Nanoparticles for Biomedical Applications IX; 89551P (2014) https://doi.org/10.1117/12.2038421
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

The main goal of this study was to investigate the sensitivity of microorganisms to combined action of blue light and iron oxide nanoparticles. Two strains of Staphylococcus aureus – methicillin-sensitive and meticillin-resistant were used. As a blue light source LED with spectral maximum at 405 nm was taken. The light exposure was ranged from 5 to 30 min. The Fe₂O₃ (diameter ∼27 nm), Fe3O4 nanoparticles (diameter ∼19 nm), and composite Fe₂O₃/TiO₂ nanoparticles (diameter ∼100 nm) were synthesized. It was shown that irradiation by blue light caused from 20% to 88% decrease in the number of microorganisms treated with nanoparticles. Morphological changes in bacterial cells after phototreatment were analyzed using scanning electron microscope.

Citation Download Citation

Elena S. Tuchina, Kristina V. Kozina, Nikita A. Shelest, Vyacheslav I. Kochubey, and Valery V. Tuchin "Iron oxide nanoparticles in different modifications for antimicrobial phototherapy", Proc. SPIE 8955, Colloidal Nanoparticles for Biomedical Applications IX, 89551P (24 March 2014); https://doi.org/10.1117/12.2038421

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