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27 June 1988 Mapping Brain Function To Brain Anatomy
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In Imaging the human brain, MRI is commonly used to reveal anatomical structure, while PET is used to reveal tissue function. This paper presents a protocol for correlating data between these two imaging modalities; this correlation can provide in vivo regional measurements of brain function which are essential to our understanding of the human brain. We propose a general protocol to standardize the acquisition and analysis of functional image data. First, MR and PET images are collected to form three-dimensional volumes of structural and functional image data. Second, these volumes of image data are corrected for distortions inherent in each imaging modality. Third, the image volumes are correlated to provide correctly aligned structural and functional images. The functional images are then mapped onto the structural images in both two-dimensional and three-dimensional representations. Finally, morphometric techniques can be used to provide statistical measures of the structure and function of the human brain.
© (1988) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
D. J. Valentino, J. C. Mazziotta, and H. K. Huang "Mapping Brain Function To Brain Anatomy", Proc. SPIE 0914, Medical Imaging II, (27 June 1988);

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