In the Netherlands a national PACS development program has been started, supported by-the Dutch Society of Radiology, and funded by the Dutch Department of Health, because of the national character of the project. Three main partners are cooperating in this development: the Utrecht University Hospital (AZU), BAZIS and Philips International (Product Division Medical Systems), with the Delft University of Technology as the main subcontractor of BAZIS. The non-profit foundation BAZIS, developing and supporting the 'ZIS' Hospital Information System (in use in some 30 Dutch hospitals now, together over 15,000 acute beds), initiated its current IMAGIS (IMAGe Information System) projects in 1984. The Dutch PACS project, in which BAZIS is participating, started in 1986. The final goal of IMAGIS is to achieve a PACS which is fully integrated with already existing hospital information systems (HIS), with support for scientific research. Both the development and operation of such a HIS-PACS include many scientific research aspects. The current efforts of BAZIS are concentrated on three main issues: diagnostic image quality evaluation (e.g. effects of data compression); modelling, software simulation and technology assessment of a prototype PACS (both general and detailed aspects); coupling and integration of PACS and HIS (e.g. the BAZIS 'ZIS'). In this paper we will refer to the following intermediate results: the psychophysical software package for Feature Evaluation And System Inspection By Logged Experiments (FEASIBLE); the modelling and simulation software package for Medical Image Representation, Archiving and Communication, Learned by Extensive Simulation (MIRACLES); first results of the coupling experiments. Finally we will outline the future direction of the IMAGIS projects.