Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms

Ricardo Gomes; João M. P. Coelho; Ana Gabriel; Pedro Vieira; Catarina Oliveira Silva; Catarina Reis

doi:10.1117/12.2063539

22 August 2014 Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms

Ricardo Gomes, João M. P. Coelho, Ana Gabriel, Pedro Vieira, Catarina Oliveira Silva, Catarina Reis

Proceedings Volume 9286, Second International Conference on Applications of Optics and Photonics; 92863Z (2014) https://doi.org/10.1117/12.2063539
Event: Second International Conference on Applications of Optics and Photonics, 2014, Aveiro, Portugal

Abstract

Although light has long being used in medicine, scattering always hindered its use. This study intends to evolve into three different frontlines: development of methodologies to concentrate light inside biological tissues, development of an optical tissue phantom and development of multifunctional gold nanoparticles with therapeutic potential for targeting anticancer drug delivery. The impact of the scattering agent (milk) concentration in the measured wavefront and spot radius is analyzed. Wavefront correction proves to be efficient in overcoming the scattering effect in the different phantoms. Future studies for developing a photodynamic approach under near-infrared wavelength are now in progress and will be further presented.

Citation Download Citation

Ricardo Gomes, João M. P. Coelho, Ana Gabriel, Pedro Vieira, Catarina Oliveira Silva, and Catarina Reis "Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms", Proc. SPIE 9286, Second International Conference on Applications of Optics and Photonics, 92863Z (22 August 2014); https://doi.org/10.1117/12.2063539

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