Three-dimensional photoacoustic and ultrasonic endoscopic imaging of two rabbit esophagi

Joon-Mo Yang; Christopher P. Favazza; Junjie Yao; Ruimin Chen; Qifa Zhou; K. Kirk Shung; Lihong V. Wang

doi:10.1117/12.2080294

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11 March 2015 Three-dimensional photoacoustic and ultrasonic endoscopic imaging of two rabbit esophagi

Joon-Mo Yang, Christopher P. Favazza, Junjie Yao, Ruimin Chen, Qifa Zhou, K. Kirk Shung, Lihong V. Wang

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Proceedings Volume 9323, Photons Plus Ultrasound: Imaging and Sensing 2015; 932334 (2015) https://doi.org/10.1117/12.2080294
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

The addition of photoacoustic endoscopy to conventional endoscopic ultrasound offers imaging capabilities that may improve diagnosis and clinical care of gastrointestinal tract diseases. In this study, using a 3.8-mm diameter dual-mode photoacoustic and ultrasonic endoscopic probe, we investigated photoacoustic and ultrasonic image features of rabbit esophagi. Specifically, we performed ex vivo imaging of intact rabbit esophagi and correlated the acquired images with histology. Without motion artifact-based limitations, we were able to utilize the full resolving power of the endoscopic device and acquire the first three-dimensional vasculature map of the esophagus and mediastinum, along with coregistered tissue density information. Here, we present the experimental results and discuss potential clinical applications of the technique.

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Joon-Mo Yang, Christopher P. Favazza, Junjie Yao, Ruimin Chen, Qifa Zhou, K. Kirk Shung, and Lihong V. Wang "Three-dimensional photoacoustic and ultrasonic endoscopic imaging of two rabbit esophagi", Proc. SPIE 9323, Photons Plus Ultrasound: Imaging and Sensing 2015, 932334 (11 March 2015); https://doi.org/10.1117/12.2080294

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