Opto-acoustic image fusion technology for diagnostic breast imaging in a feasibility study

Jason Zalev; Bryan Clingman; Don Herzog; Tom Miller; Michael Ulissey M.D.; A. Thomas Stavros M.D.; Alexander Oraevsky; Philip Lavin; Kenneth Kist M.D.; N. Carol Dornbluth M.D.; Pamela Otto M.D.

doi:10.1117/12.2081679

17 March 2015 Opto-acoustic image fusion technology for diagnostic breast imaging in a feasibility study

Jason Zalev, Bryan Clingman, Don Herzog, Tom Miller, Michael Ulissey M.D., A. Thomas Stavros M.D., Alexander Oraevsky, Philip Lavin, Kenneth Kist M.D., N. Carol Dornbluth M.D., Pamela Otto M.D.

Author Affiliations +

Proceedings Volume 9419, Medical Imaging 2015: Ultrasonic Imaging and Tomography; 941909 (2015) https://doi.org/10.1117/12.2081679
Event: SPIE Medical Imaging, 2015, Orlando, Florida, United States

Abstract

Functional opto-acoustic (OA) imaging was fused with gray-scale ultrasound acquired using a specialized duplex handheld probe. Feasibility Study findings indicated the potential to more accurately characterize breast masses for cancer than conventional diagnostic ultrasound (CDU). The Feasibility Study included OA imagery of 74 breast masses that were collected using the investigational Imagio® breast imaging system. Superior specificity and equal sensitivity to CDU was demonstrated, suggesting that OA fusion imaging may potentially obviate the need for negative biopsies without missing cancers in a certain percentage of breast masses. Preliminary results from a 100 subject Pilot Study are also discussed. A larger Pivotal Study (n=2,097 subjects) is underway to confirm the Feasibility Study and Pilot Study findings.

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Jason Zalev, Bryan Clingman, Don Herzog, Tom Miller, Michael Ulissey M.D., A. Thomas Stavros M.D., Alexander Oraevsky, Philip Lavin, Kenneth Kist M.D., N. Carol Dornbluth M.D., and Pamela Otto M.D. "Opto-acoustic image fusion technology for diagnostic breast imaging in a feasibility study", Proc. SPIE 9419, Medical Imaging 2015: Ultrasonic Imaging and Tomography, 941909 (17 March 2015); https://doi.org/10.1117/12.2081679

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