Multisense chip: continuously working air monitoring system: An integrated system for the detection of airborne biological pathogens on molecular and immunological level

Claudia Gärtner; Holger Becker; Nadine Hlawatsch; Richard Klemm; Sebastian Schattschneider; Christian Moche

doi:10.1117/12.2178923

2 June 2015 Multisense chip: continuously working air monitoring system: An integrated system for the detection of airborne biological pathogens on molecular and immunological level

Claudia Gärtner, Holger Becker, Nadine Hlawatsch, Richard Klemm, Sebastian Schattschneider, Christian Moche

Author Affiliations +

Proceedings Volume 9455, Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XVI; 94550B (2015) https://doi.org/10.1117/12.2178923
Event: SPIE Defense + Security, 2015, Baltimore, MD, United States

Abstract

Lab-on-a-chip systems are very promising approach for a decentralized continuous pathogen monitoring. The overall presented system consisting of a microtiter plate sized consumable and the respective instrument allows for the detection of airborne biological pathogen. The target pathogens to be detected are Yersinia pestis, Francisella tularensis, Burkholderia mallei, Burkholderia pseudomallei, Brucella melitensis, Brucella abortis, Coxiella burnetti, and Bacillus anthracis. Important to stress that the technical platform can be easily expanded to further pathogens. In this paper the development of a fully integrated system for the 8-plex detection of bacterial pathogens will be presented. Two exceptional features are combined in this device: The overall system allows for the permanent sampling and analysis of airborne biological pathogens and combines the detection of the respective bacteria on molecular and immunological level. The overall system consisting of chip and instrument and the biological procedures embedded on chip will be presented.

Citation Download Citation

Claudia Gärtner, Holger Becker, Nadine Hlawatsch, Richard Klemm, Sebastian Schattschneider, and Christian Moche "Multisense chip: continuously working air monitoring system: An integrated system for the detection of airborne biological pathogens on molecular and immunological level", Proc. SPIE 9455, Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Sensing XVI, 94550B (2 June 2015); https://doi.org/10.1117/12.2178923

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available