A biopsymeter to support the diagnostic procedure of skin samples

Valeria Fioravanti; Shailendra Chandrashekar; Lukas Brandhoff; Daniela Pucciarelli; Sander van den Driesche; Heimo Breiteneder; Christine Hafner; Michael J. Vellekoop

doi:10.1117/12.2178500

1 June 2015 A biopsymeter to support the diagnostic procedure of skin samples

Valeria Fioravanti, Shailendra Chandrashekar, Lukas Brandhoff, Daniela Pucciarelli, Sander van den Driesche, Heimo Breiteneder, Christine Hafner, Michael J. Vellekoop

Author Affiliations +

Proceedings Volume 9518, Bio-MEMS and Medical Microdevices II; 95180A (2015) https://doi.org/10.1117/12.2178500
Event: SPIE Microtechnologies, 2015, Barcelona, Spain

Abstract

We present an infrared biopsymeter to assist pathologists in the diagnosis of melanoma presence in skin biopsies. The designed and realized system combines the features of visual inspection and physical sensing to reduce false positives and false negatives occurring during standard histopathological analyses. The biopsymeter determines the CH₂-stretch ratio by infrared absorbance measurements of skin biopsies. Investigations conducted with the biopsymeter shows that malignant melanomas and melanoma metastases have higher CH₂-stretch ratio values compared to healthy skin tissues.

Citation Download Citation

Valeria Fioravanti, Shailendra Chandrashekar, Lukas Brandhoff, Daniela Pucciarelli, Sander van den Driesche, Heimo Breiteneder, Christine Hafner, and Michael J. Vellekoop "A biopsymeter to support the diagnostic procedure of skin samples", Proc. SPIE 9518, Bio-MEMS and Medical Microdevices II, 95180A (1 June 2015); https://doi.org/10.1117/12.2178500

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