Registration of intracellular pH in cancer cells with genetically encoded ratiometric sensor

Irina Druzhkova; Marina Shirmanova; Maria Lukina; Varvara Dudenkova; Tatiyana Sergeeva; Vsevolod Belousov; Sergey Lukyanov; Elena Zagaynova

doi:10.1117/12.2184756

15 July 2015 Registration of intracellular pH in cancer cells with genetically encoded ratiometric sensor

Irina Druzhkova, Marina Shirmanova, Maria Lukina, Varvara Dudenkova, Tatiyana Sergeeva, Vsevolod Belousov, Sergey Lukyanov, Elena Zagaynova

Author Affiliations +

Proceedings Volume 9537, Clinical and Biomedical Spectroscopy and Imaging IV; 953710 (2015) https://doi.org/10.1117/12.2184756
Event: European Conferences on Biomedical Optics, 2015, Munich, Germany

Abstract

This work is aimed at the development of new approach to register intracellular pH with genetically encoded ratiometric sensor. Intracellular pH of cancer cells was studied in vitro and in vivo. Changes of intracellular pH under conditions of co-culturing with fibroblast were investigated.

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Irina Druzhkova, Marina Shirmanova, Maria Lukina, Varvara Dudenkova, Tatiyana Sergeeva, Vsevolod Belousov, Sergey Lukyanov, and Elena Zagaynova "Registration of intracellular pH in cancer cells with genetically encoded ratiometric sensor", Proc. SPIE 9537, Clinical and Biomedical Spectroscopy and Imaging IV, 953710 (15 July 2015); https://doi.org/10.1117/12.2184756

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