Time resolved optical detection for white matter lesion detection: preclinical tests on macaque brains and MRI co-registration

A. Planat-Chrétien; M. Berger; L. Hervé; L. Watroba; J. Demilly; J. Flament; L. Stimmer; P. Aubourg; J.-M. Dinten

doi:10.1117/12.2183733

16 July 2015 Time resolved optical detection for white matter lesion detection: preclinical tests on macaque brains and MRI co-registration

A. Planat-Chrétien, M. Berger, L. Hervé, L. Watroba, J. Demilly, J. Flament, L. Stimmer, P. Aubourg, J.-M. Dinten

Author Affiliations +

Proceedings Volume 9538, Diffuse Optical Imaging V; 953806 (2015) https://doi.org/10.1117/12.2183733
Event: European Conferences on Biomedical Optics, 2015, Munich, Germany

Abstract

We conducted a preclinical assessment on young macaques aimed at detecting white matter lesions. We present the protocol we implemented to achieve the lesions detection using a bedside non-invasive optical-based Time-Resolved instrumentation we have optimized for this purpose. We validated the reconstructed 3D absorption map with co-registration of MRI data.

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A. Planat-Chrétien, M. Berger, L. Hervé, L. Watroba, J. Demilly, J. Flament, L. Stimmer, P. Aubourg, and J.-M. Dinten "Time resolved optical detection for white matter lesion detection: preclinical tests on macaque brains and MRI co-registration", Proc. SPIE 9538, Diffuse Optical Imaging V, 953806 (16 July 2015); https://doi.org/10.1117/12.2183733

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