Impact of terahertz radiation on the epithelialization rate of scarified cornea

I. A. Geyko; O. A. Smolyanskaya; M. I. Sulatsky; S. E. Parakhuda; E. A. Sedykh; E. L. Odlyanitskiy; M. K. Khodzitsky; A. G. Zabolotniy

doi:10.1117/12.2183866

15 July 2015 Impact of terahertz radiation on the epithelialization rate of scarified cornea

I. A. Geyko, O. A. Smolyanskaya, M. I. Sulatsky, S. E. Parakhuda, E. A. Sedykh, E. L. Odlyanitskiy, M. K. Khodzitsky, A. G. Zabolotniy

Author Affiliations +

Proceedings Volume 9542, Medical Laser Applications and Laser-Tissue Interactions VII; 95420E (2015) https://doi.org/10.1117/12.2183866
Event: European Conferences on Biomedical Optics, 2015, Munich, Germany

Abstract

We revealed that after exposure of scarified cornea of rabbits to low-intensity pulsed terahertz radiation 0.1 to 1.8 THz a positive effect on epithelization triggered within the first hours was higher compared to non-irradiated cornea. However, while elevating power of terahertz radiation up to 60.8 nW it resulted in retarding epithelialization process. At that, irradiation did not affect timeframe of complete corneal epithelialization. During experiments it was found that terahertz radiation was well tolerated, exhibited no toxic and allergic reactions or resulted in pathohistological changes in the eye tissues. Also, low-intensity terahertz radiation did not affect normal physiological functions of the eyes and facilitated to re-epithelialization of scarified eyes in rabbits.

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I. A. Geyko, O. A. Smolyanskaya, M. I. Sulatsky, S. E. Parakhuda, E. A. Sedykh, E. L. Odlyanitskiy, M. K. Khodzitsky, and A. G. Zabolotniy "Impact of terahertz radiation on the epithelialization rate of scarified cornea ", Proc. SPIE 9542, Medical Laser Applications and Laser-Tissue Interactions VII, 95420E (15 July 2015); https://doi.org/10.1117/12.2183866

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