Nanoscale patterning of poly (L-lactic acid) films with nanoimprinting methods

Akshit Peer; Rabin Dhakal; Rana Biswas; Jaeyoun Kim

doi:10.1117/12.2188888

20 August 2015 Nanoscale patterning of poly (L-lactic acid) films with nanoimprinting methods

Akshit Peer, Rabin Dhakal, Rana Biswas, Jaeyoun Kim

Proceedings Volume 9556, Nanoengineering: Fabrication, Properties, Optics, and Devices XII; 95560X (2015) https://doi.org/10.1117/12.2188888
Event: SPIE Nanoscience + Engineering, 2015, San Diego, California, United States

Abstract

Biological applications can benefit from nanoscale texturing of materials for biomedical functions. Texturing of biomaterials can increase the available surface area so that they can be coated with larger doses of therapeutic agents. We demonstrate nano-texturing of poly (L-lactic acid) (PLLA) – a prototypical material commonly used for drug-eluting coronary stents and as a template for cell growth. A master pattern consisting of a periodic array was transferred to a PDMS mold. Drop-casting PLLA achieves the best transfer of patterns, with nanoarrays of holes with pitch ~700 nm. Nanoimprinting the PLLA films results in shallower and less resolved features.

Conference Presentation

Citation Download Citation

Akshit Peer, Rabin Dhakal, Rana Biswas, and Jaeyoun Kim "Nanoscale patterning of poly (L-lactic acid) films with nanoimprinting methods", Proc. SPIE 9556, Nanoengineering: Fabrication, Properties, Optics, and Devices XII, 95560X (20 August 2015); https://doi.org/10.1117/12.2188888

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