Paper
10 August 2015 Biochemical sensing application based on optical fiber evanescent wave sensor
Xiaoyi Lv, Jiaqing Mo, Liang Xu, Zhenhong Jia
Author Affiliations +
Proceedings Volume 9620, 2015 International Conference on Optical Instruments and Technology: Optical Sensors and Applications; 96200T (2015) https://doi.org/10.1117/12.2191430
Event: International Conference on Optical Instruments and Technology 2015, 2015, Beijing, China
Abstract
We have designed a novel evanescent field fiber optic biosensors with porous silicon dioxide cladding. The pore size of porous silicon dioxide cladding is about 100 nm in diameter. Biological molecules were immobilized to the porous silicon dioxide cladding used APTES and glutaraldehyde. Refractive index of cladding used Bruggemann's effective medium theory. We carried out simulations of changing in light intensity in optical fiber before and after chemical coupling of biomolecules. This novel optical fiber evanescent wave biosensor has a great potential in clinical chemistry for rapid and convenient determination of biological molecule.
© (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Xiaoyi Lv, Jiaqing Mo, Liang Xu, and Zhenhong Jia "Biochemical sensing application based on optical fiber evanescent wave sensor", Proc. SPIE 9620, 2015 International Conference on Optical Instruments and Technology: Optical Sensors and Applications, 96200T (10 August 2015); https://doi.org/10.1117/12.2191430
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KEYWORDS
Cladding

Silica

Optical fibers

Biosensors

Molecular biology

Molecules

Refractive index

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