Optical coherence tomography imaging to analyze biofilm thickness from distal to proximal regions of the endotracheal tubes

Robert E. Dunn; Andrew E. Heidari; Samer Moghaddam M.D.; Mengke Zhang; Changhoon Han; Kyung-Jin Oh; Steve Leven; Matthew Brenner M.D.; Carl Genberg; Zhongping Chen

doi:10.1117/12.2213247

8 March 2016 Optical coherence tomography imaging to analyze biofilm thickness from distal to proximal regions of the endotracheal tubes

Robert E. Dunn, Andrew E. Heidari, Samer Moghaddam M.D., Mengke Zhang, Changhoon Han, Kyung-Jin Oh, Steve Leven, Matthew Brenner M.D., Carl Genberg, Zhongping Chen

Author Affiliations +

Proceedings Volume 9691, Endoscopic Microscopy XI; and Optical Techniques in Pulmonary Medicine III; 96911G (2016) https://doi.org/10.1117/12.2213247
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

The development of nosocomial ventilator-associated pneumonia (VAP) has been linked to the presence of specific bacteria found in the biofilm that develops in intubated endotracheal tubes of critical care patients. Presence of biofilm has been difficult to assess clinically. Here, we use Optical coherence tomography (OCT), to visualize the biofilm at both the proximal and distal tips. Ultimately, the goal will be to determine if OCT can be a tool to visualize biofilm development and potential interventions to reduce the incidence of VAP.

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Robert E. Dunn, Andrew E. Heidari, Samer Moghaddam M.D., Mengke Zhang, Changhoon Han, Kyung-Jin Oh, Steve Leven, Matthew Brenner M.D., Carl Genberg, and Zhongping Chen "Optical coherence tomography imaging to analyze biofilm thickness from distal to proximal regions of the endotracheal tubes", Proc. SPIE 9691, Endoscopic Microscopy XI; and Optical Techniques in Pulmonary Medicine III, 96911G (8 March 2016); https://doi.org/10.1117/12.2213247

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