Towards multimodal detection of melanoma thickness based on optical coherence tomography and optoacoustics

M. Rahlves; A. Varkentin; J. Stritzel; E. Blumenröther; M. Mazurenka; M. Wollweber; B. Roth

doi:10.1117/12.2213132

7 March 2016 Towards multimodal detection of melanoma thickness based on optical coherence tomography and optoacoustics

M. Rahlves, A. Varkentin, J. Stritzel, E. Blumenröther, M. Mazurenka, M. Wollweber, B. Roth

Proceedings Volume 9701, Multimodal Biomedical Imaging XI; 97010F (2016) https://doi.org/10.1117/12.2213132
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Melanoma skin cancer has one of the highest mortality rates of all types of cancer if not detected at an early stage. The survival rate is highly dependent on its penetration depth, which is commonly determined by histopathology. In this work, we aim at combining optical coherence tomography and optoacoustic as a non-invasive all-optical method to measure the penetration depth of melanoma. We present our recent achievements to setup a handheld multimodal device and also results from first in vivo measurements on healthy and cancerous skin tissue, which are compared to measurements obtained by ultrasound and histopathology.

Citation Download Citation

M. Rahlves, A. Varkentin, J. Stritzel, E. Blumenröther, M. Mazurenka, M. Wollweber, and B. Roth "Towards multimodal detection of melanoma thickness based on optical coherence tomography and optoacoustics", Proc. SPIE 9701, Multimodal Biomedical Imaging XI, 97010F (7 March 2016); https://doi.org/10.1117/12.2213132

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