A novel method for sensing metastatic cells in the CSF of pediatric population with medulloblastoma by frequency domain FLIM system

Gilad Yahav; Dror Fixler; Sivan Gershanov; Nitza Goldenberg-Cohen

doi:10.1117/12.2208014

22 April 2016 A novel method for sensing metastatic cells in the CSF of pediatric population with medulloblastoma by frequency domain FLIM system

Gilad Yahav, Dror Fixler, Sivan Gershanov, Nitza Goldenberg-Cohen

Author Affiliations +

Proceedings Volume 9721, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII; 97210T (2016) https://doi.org/10.1117/12.2208014
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Brain tumors are the second leading cause of cancer-related deaths in children, after leukemia. Patients with cancer in the central nervous system have a very low recovery rate. Today known imaging and cytology techniques are not always sensitive enough for an early detection of both tumor and its metastatic spread, moreover the detection is generally limited, reviewer dependent and takes a relatively long time. Medulloblastoma (MB) is the most common malignant brain tumor in children. The aim of our talk is to present the frequency domain fluorescence lifetime imaging microscopy system as a possible method for an early detection of MB and its metastatic spread in the cerebrospinal fluids within the pediatric population.

Conference Presentation

Citation Download Citation

Gilad Yahav, Dror Fixler, Sivan Gershanov, and Nitza Goldenberg-Cohen "A novel method for sensing metastatic cells in the CSF of pediatric population with medulloblastoma by frequency domain FLIM system", Proc. SPIE 9721, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII, 97210T (22 April 2016); https://doi.org/10.1117/12.2208014

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