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19 May 2016 Progressive anomaly detection in medical data using vital sign signals
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Vital Sign Signals (VSSs) have been widely used for medical data analysis. One classic approach is to use Logistic Regression Model (LRM) to describe data to be analyzed. There are two challenging issues from this approach. One is how many VSSs needed to be used in the model since there are many VSSs can be used for this purpose. Another is that once the number of VSSs is determined, the follow-up issue what these VSSs are. Up to date these two issues are resolved by empirical selection. This paper addresses these two issues from a hyperspectral imaging perspective. If we view a patient with collected different vital sign signals as a pixel vector in hyperspectral image, then each vital sign signal can be considered as a particular band. In light of this interpretation each VSS can be ranked by band prioritization commonly used by band selection in hyperspectral imaging. In order to resolve the issue of how many VSSs should be used for data analysis we further develop a Progressive Band Processing of Anomaly Detection (PBPAD) which allows users to detect anomalies in medical data using prioritized VSSs one after another so that data changes between bands can be dictated by profiles provided by PBPAD. As a result, there is no need of determining the number of VSSs as well as which VSS should be used because all VSSs are used in their prioritized orders. To demonstrate the utility of PBPAD in medical data analysis anomaly detection is implemented as PBP to find anomalies which correspond to abnormal patients. The data to be used for experiments are data collected in University of Maryland, School of Medicine, Shock Trauma Center (STC). The results will be evaluated by the results obtained by Logistic Regression Model (LRM).
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Cheng Gao, Li-Chien Lee, Yao Li, Chein-I Chang, Peter Hu, and Colin Mackenzie "Progressive anomaly detection in medical data using vital sign signals", Proc. SPIE 9874, Remotely Sensed Data Compression, Communications, and Processing XII, 98740I (19 May 2016);

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