Adaptive optics: optical coherence tomography imaging of the inner retina in multiple sclerosis

Daniel X. Hammer; Zhuolin Liu; Katherine Kovalick; Osamah Saeedi; Daniel M. Harrison

doi:10.1117/12.2608765

7 March 2022 Adaptive optics: optical coherence tomography imaging of the inner retina in multiple sclerosis

Daniel X. Hammer, Zhuolin Liu, Katherine Kovalick, Osamah Saeedi, Daniel M. Harrison

Author Affiliations +

Proceedings Volume PC11941, Ophthalmic Technologies XXXII; PC1194106 (2022) https://doi.org/10.1117/12.2608765
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Multiple sclerosis (MS) is a debilitating autoimmune disease characterized by lesions found in different regions of the central nervous system caused by overactive immune cells. MS also manifests in the retina, in which optic nerve pathology (such as optic neuritis) and neurodegenerative processes can affect inner retinal cells and structures. We observed the inner retina to be profoundly affected by MS, including nerve fiber bundle thinning, enlarged and lower density retinal ganglion cells, and the presence of microcysts. Longitudinal quantification of inner retinal changes enabled by AO-OCT may help accelerate the development of novel therapies for MS patients.

Conference Presentation

Citation Download Citation

Daniel X. Hammer, Zhuolin Liu, Katherine Kovalick, Osamah Saeedi, and Daniel M. Harrison "Adaptive optics: optical coherence tomography imaging of the inner retina in multiple sclerosis", Proc. SPIE PC11941, Ophthalmic Technologies XXXII, PC1194106 (7 March 2022); https://doi.org/10.1117/12.2608765

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE