Functional neuroimaging of the corneal nerves longitudinally and in vivo

Matthew T. McPheeters; Brecken J. Blackburn; William J. Dupps; Andrew M. Rollins; Michael W. Jenkins

doi:10.1117/12.2609039

7 March 2022 Functional neuroimaging of the corneal nerves longitudinally and in vivo

Matthew T. McPheeters, Brecken J. Blackburn, William J. Dupps, Andrew M. Rollins, Michael W. Jenkins

Proceedings Volume PC11941, Ophthalmic Technologies XXXII; PC119410E (2022) https://doi.org/10.1117/12.2609039
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

The structure and composition of the corneal nerves in health and disease have been extensively studied, however, study of corneal nerve function in living systems has been challenging and limited. Here, we demonstrate non-contact, longitudinal imaging of in vivo murine corneal nerve signaling and in vivo stimulus-response. These developments have the potential to allow for new studies of changes to corneal nerve function in disease and damage, and for better assessment of therapies to treat dysfunction and diminished nerve function.

Conference Presentation

Citation Download Citation

Matthew T. McPheeters, Brecken J. Blackburn, William J. Dupps, Andrew M. Rollins, and Michael W. Jenkins "Functional neuroimaging of the corneal nerves longitudinally and in vivo", Proc. SPIE PC11941, Ophthalmic Technologies XXXII, PC119410E (7 March 2022); https://doi.org/10.1117/12.2609039

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