Localizing and quantifying macular pigments in humans with visible light optical coherence tomography (OCT)

Alok Gupta; Ruoyu Meng; Vivek Srinivasan

doi:10.1117/12.2650759

17 March 2023 Localizing and quantifying macular pigments in humans with visible light optical coherence tomography (OCT)

Alok Gupta, Ruoyu Meng, Vivek Srinivasan

Author Affiliations +

Proceedings Volume PC12360, Ophthalmic Technologies XXXIII; PC123600Y (2023) https://doi.org/10.1117/12.2650759
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Here we present a new approach to quantify macular pigments and importantly, localize them in depth within the human retina in vivo. The approach utilizes visible light Optical Coherence Tomography (OCT) imaging with multiple combined superluminescent diodes, with energy concentrated at discrete red, green, and blue wavelength bands. Imaging simultaneously with red and blue wavelengths, we reveal the expected distribution of macular pigment optical density with a peak at or near the foveal center. Imaging simultaneously with red and green wavelengths, we localize macular pigments in depth to the region beneath the foveal pit, inner to the photoreceptors.

Conference Presentation

Citation Download Citation

Alok Gupta, Ruoyu Meng, and Vivek Srinivasan "Localizing and quantifying macular pigments in humans with visible light optical coherence tomography (OCT)", Proc. SPIE PC12360, Ophthalmic Technologies XXXIII, PC123600Y (17 March 2023); https://doi.org/10.1117/12.2650759

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