Interferometric thermometry of ocular tissues for retinal laser therapy

Yueming Zhuo; David Veysset; Junya Hattori; Mohajeet Bhuckory; Daniel V. Palanker

doi:10.1117/12.2650421

17 March 2023 Interferometric thermometry of ocular tissues for retinal laser therapy

Yueming Zhuo, David Veysset, Junya Hattori, Mohajeet Bhuckory, Daniel V. Palanker

Proceedings Volume PC12360, Ophthalmic Technologies XXXIII; PC1236011 (2023) https://doi.org/10.1117/12.2650421
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Monitoring the tissue temperature is highly desirable for predictable and reproducible retinal laser therapy. We demonstrate that the temperature rise can be determined using pOCT imaging of the optical path length changes within the laser spot relative to the non-heated region. A temperature-sensitive fluorescent dye was used for initial calibration. By matching the thermal expansion across the beam width and along the full course of heating and cooling, the temperature distribution can be determined with a precision of about 10% (under 2℃ with a peak heating of 17℃) following a single laser pulse of 20ms in duration.

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Yueming Zhuo, David Veysset, Junya Hattori, Mohajeet Bhuckory, and Daniel V. Palanker "Interferometric thermometry of ocular tissues for retinal laser therapy", Proc. SPIE PC12360, Ophthalmic Technologies XXXIII, PC1236011 (17 March 2023); https://doi.org/10.1117/12.2650421

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KEYWORDS

Laser tissue interaction

Laser therapeutics

Optical coherence tomography

Phase measurement

Absorption

Pulsed laser operation

Tissue optics

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