Multispectral filter arrays for early cancer detection in endoscopy

Katie-Lou White; Calum Williams; Lina Hacker; Sarah E. Bohndiek

doi:10.1117/12.2648855

17 March 2023 Multispectral filter arrays for early cancer detection in endoscopy

Katie-Lou White, Calum Williams, Lina Hacker, Sarah E. Bohndiek

Author Affiliations +

Proceedings Volume PC12361, Molecular-Guided Surgery: Molecules, Devices, and Applications IX; PC1236105 (2023) https://doi.org/10.1117/12.2648855
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Standard-of-care endoscopy and laparoscopy require multiple cameras to enable molecular imaging, which leads to challenges of 3D image registration and overlay. To address this, we are developing a targeted multispectral imaging (MSI) camera using custom multispectral filter arrays integrated onto image sensors. The design augments RGB-Bayer filters with sub-pixel narrowband filters, thereby maintaining white-light imaging through pixel binning while adding MSI contrast enhancement. Prototypes were tested by imaging tissue-mimicking phantoms containing blood of varied oxygenation, ICG dye and color charts. Future work will examine the translation potential for chip-on-tip endoscopy.

Conference Presentation

Citation Download Citation

Katie-Lou White, Calum Williams, Lina Hacker, and Sarah E. Bohndiek "Multispectral filter arrays for early cancer detection in endoscopy", Proc. SPIE PC12361, Molecular-Guided Surgery: Molecules, Devices, and Applications IX, PC1236105 (17 March 2023); https://doi.org/10.1117/12.2648855

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