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9 March 2023 Monitoring microscopic disease progression in pulmonary fibrosis using endobronchial optical coherence tomography
Sreyankar Nandy, Sarita Berigei, Bess Flashner M.D., Rebecca Raphaely M.D., Amita Sharma M.D., Amalia Decoursey, Satomi Yamamoto-mcguire M.D., Caroline Fromson, Mamary Kone, Stephanie Halks, Kevin Reyes, Kimberley Schreefer, Colleen Keyes M.D., Lida Hariri M.D.
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Proceedings Volume PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; PC1236705 (2023) https://doi.org/10.1117/12.2653115
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
The ability to monitor disease progression over time is critical to inform patient care and prognosis, especially in usual interstitial pneumonia (UIP), the histopathological pattern seen in idiopathic pulmonary fibrosis (IPF). HRCT is limited in resolution to detect disease changes on a microscopic level, and surgical lung biopsy (SLB) has high risk of morbidity and mortality precluding its use to assess progression. Endobronchial optical coherence tomography (EB-OCT) is a bronchoscopic, minimally-invasive, high-resolution imaging method that accurately detects microscopic ILD features and is repeatable. Here, we evaluate the utility of repeat EB-OCT for monitoring microscopic disease progression in UIP/IPF.
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Sreyankar Nandy, Sarita Berigei, Bess Flashner M.D., Rebecca Raphaely M.D., Amita Sharma M.D., Amalia Decoursey, Satomi Yamamoto-mcguire M.D., Caroline Fromson, Mamary Kone, Stephanie Halks, Kevin Reyes, Kimberley Schreefer, Colleen Keyes M.D., and Lida Hariri M.D. "Monitoring microscopic disease progression in pulmonary fibrosis using endobronchial optical coherence tomography", Proc. SPIE PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, PC1236705 (9 March 2023); https://doi.org/10.1117/12.2653115
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KEYWORDS
Optical coherence tomography
Pulmonary fibrosis
Lung
Biopsy
Cancer
Computed tomography
Lung cancer
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