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We propose a B-scan-wise- multi-focus average method (B-MFA) to suppress multiple scattering noise for in-vivo imaging. This method uses only multiple B-scans with modulated focus position for complex averaging, and a one-dimensional computational refocusing is applied to cancel the defocus in each B-scan. To validate the proposed method, ten medaka fish were measured in-vivo without anesthesia. The results show that B-MFA can enhance the OCT image contrast in the deep regions.
Yiqiang Zhu,Lida Zhu,Shuichi Makita,Yiheng Lim,Yu Guo, andYoshiaki Yasuno
"Multiple scattering suppression for in vivo OCT measurement by B-scan-wise-multi-focus averaging method", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC1283013 (13 March 2024); https://doi.org/10.1117/12.3003699
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Yiqiang Zhu, Lida Zhu, Shuichi Makita, Yiheng Lim, Yu Guo, Yoshiaki Yasuno, "Multiple scattering suppression for in vivo OCT measurement by B-scan-wise-multi-focus averaging method," Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC1283013 (13 March 2024); https://doi.org/10.1117/12.3003699