Ultra-wideband optical coherence elastography from acoustic to ultrasonic frequencies

Xu Feng; Guo-Yang Li; Seok-Hyun Yun

doi:10.1117/12.2691484

13 March 2024 Ultra-wideband optical coherence elastography from acoustic to ultrasonic frequencies

Xu Feng, Guo-Yang Li, Seok-Hyun Yun

Proceedings Volume PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII; PC1283026 (2024) https://doi.org/10.1117/12.2691484
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Optical coherence elastography has emerged as a powerful non-invasive tool for quantifying tissue biomechanics; however, traditional elastography techniques have been limited by a maximum wave frequency below 10 kHz, resulting in compromised temporal and spatial resolution. Here, we present an optical coherence elastography technique capable of extending the frequency range to the MHz regime. Our system enables the measurement of materials across a broad spectrum of stiffness, from the hydrogel to the bone. The rich broadband dispersion of surface waves allowed us to profile the depth-dependent shear modulus in cartilages ex vivo and human skin in vivo with sub-mm anatomical resolution.

Conference Presentation

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Xu Feng, Guo-Yang Li, and Seok-Hyun Yun "Ultra-wideband optical coherence elastography from acoustic to ultrasonic frequencies", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC1283026 (13 March 2024); https://doi.org/10.1117/12.2691484

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KEYWORDS

Elastography

Optical coherence

Acoustics

Ultrasonics

Acoustic waves

Algorithm development

Tissues

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