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13 March 2024 Bioresorbable multifunctional fiber-optic devices for theranostic and monitoring of tumor
Jawad T. Pandayil, Nadia G. Boetti, Lorenzo Cortese, Vamshi Damagatla, Davide Janner, Turgut Durduran, Antonio Pifferi, Diego Pugliese
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Proceedings Volume PC12835, Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV; PC1283503 (2024) https://doi.org/10.1117/12.3002672
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
Calcium phosphate glass based single-mode and multi-mode bioresorbable optical fibers were in-house manufactured. Ex-vivo studies were then conducted to test the suitability of these fibers for time gated diffuse optics spectroscopy, photodynamic therapy and diffuse correlation spectroscopy applications which can be respectively employed for the diagnosis, treatment, and monitoring of malignant tissues. The results demonstrated the potential of calcium phosphate glass-based fiber optic devices towards the realization of an implantable multi-functional class of devices with functionalities ranging from cancer detection to monitoring of the healing process all integrated into a single bioresorbable platform. Acknowledgement: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 860185
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Jawad T. Pandayil, Nadia G. Boetti, Lorenzo Cortese, Vamshi Damagatla, Davide Janner, Turgut Durduran, Antonio Pifferi, and Diego Pugliese "Bioresorbable multifunctional fiber-optic devices for theranostic and monitoring of tumor", Proc. SPIE PC12835, Optical Fibers and Sensors for Medical Diagnostics, Treatment, and Environmental Applications XXIV, PC1283503 (13 March 2024); https://doi.org/10.1117/12.3002672
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KEYWORDS
Fiber optics
Tumors
Biomedical applications
Calcium
Optical fibers
Phosphates
Photodynamic therapy
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