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1 September 2010 Three-dimensional optical imaging of microvascular networks within intact lymph node in vivo
Yeongri Jung, Zhongwei Zhi, Ruikang K. Wang
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Journal of Biomedical Optics, Vol. 15, Issue 5, 050501 (September 2010). https://doi.org/10.1117/1.3496301
Abstract
Sentinel lymph nodes (SLNs) are the first lymph nodes to drain wastes originated from cancerous tissue. There is a need for an in vivo imaging method that can image the intact SLN to further our understanding of its normal as well as abnormal functions. We report the use of ultrahigh sensitive optical microangiography (UHS-OMAG) to image functional microvascular and lymphatic vessel networks that innervate the intact lymph node in mice in vivo. The promising results show a potential role of UHS-OMAG in the future understanding and diagnosis of the SLN involvement in cancer development.
©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)
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Yeongri Jung, Zhongwei Zhi, and Ruikang K. Wang "Three-dimensional optical imaging of microvascular networks within intact lymph node in vivo," Journal of Biomedical Optics 15(5), 050501 (1 September 2010). https://doi.org/10.1117/1.3496301
Published: 1 September 2010
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Cited by 29 scholarly publications and 2 patents.
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KEYWORDS
Lymphatic system
Tissues
In vivo imaging
3D image processing
Blood vessels
Optical coherence tomography
Blood circulation
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