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2 July 2013 Adaptive Optics for Biological Imaging
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Abstract
It is fascinating how optical technology transfers among disparate fields of science and engineering. The history of adaptive optics is a good case study. The story begins in 1953 when a visionary, Horace Babcock, who was an astronomer at the Mount Wilson and the Palomar observatories, proposed a method based on adaptive optics to correct in real time the atmospheric distortions that degraded ground-based telescope images. All ground-based telescopes suffer from atmospheric turbulence, which causes time-dependent inhomogeneities in the air refractive index. They are caused by nonstationary random processes. The wind shears mix various atmospheric layers and the temperature inhomogeneities result in time-dependent variations in the refractive index of the air. They distort the wavefronts and thus degrade the image. One alternative is space-based telescopes such as the Hubble Space Telescope. Another is to implement Babcock’s idea of a closed-loop system incorporating a wavefront sensor and a deformable mirror that can introduce real-time changes in the wavefront to compensate for the aberrations introduced by the atmospheric turbulence. Babcock’s prescient ideas were developed into instrumentation in the mid-1970s and in 1982 the Defense Advanced Research Projects Agency (DARPA) working with the United States Air Force completed a real-time adaptive optics system integrated with an optical telescope on Maui in Hawaii. The motivation was to obtain high-resolution images of Soviet satellites. One common wavefront sensor is the Shack-Hartmann wavefront sensor, which works with white light and also with extended sources (such as the Sun). The closed-loop adaptive optics system involves computer wavefront reconstruction, which is a classical inverse problem whose solution can be found, but the solution cannot be proved to be unique.
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
Barry R. Masters "Adaptive Optics for Biological Imaging," Journal of Biomedical Optics 18(7), 079901 (2 July 2013). https://doi.org/10.1117/1.JBO.18.7.079901
Published: 2 July 2013
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Cited by 1 scholarly publication.
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KEYWORDS
Adaptive optics

Wavefront sensors

Space telescopes

Wavefronts

Atmospheric optics

Atmospheric turbulence

Deformable mirrors

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