Moscow megapolis is among the world's 20 largest megacities. Intensive air emissions of pollutants affect not only the state of the atmosphere above the megapolis, but also far beyond its limits. To obtain diagnostic and predictive assessments of this impact intensive measurements of air pollutants as well as chemical transport simulations are developed. Agreement of parameters used in chemical transport models (CTMs) with experimental results continues to be an important task. We present preliminary results of a comparison of the measured by DOAS technique and simulated by COSMO-Ru7-Art NO2 integral contents (IC) in the atmospheric boundary layer (ABL) at Zvenigorod Scientific Station (ZSS) located in 38 km west from Moscow. The comparison covers summer seasons of 2015 and 2016. The measured NO2 IC in the ABL observed at ZSS does not exceed 0.5×1016 molec×cm-2 in background conditions of the atmosphere when non-east wind direction dominated. It grows up to 4×1016 molec×cm-2 when polluted air masses come from Moscow megacity. Simulated NO2 IC has similar behavior. In general, a good agreement between measured and simulated datasets is observed. Usage of improved algorithm for NO2 IC measurements allows to compare measured and simulated diurnal variations of NO2 IC in the ABL. Increasing of the sample of analyzed data allows to reveal and analyze measured and simulated weekly cycle of NO2 IC in the ABL. Observed disagreements between measured and simulated characteristics of NO2 IC variations can be a source for improving of NO2 emission inventory.