SignificanceDiabetes is a prevalent disease worldwide that can cause severe health problems. Accurate blood glucose detection is crucial for diabetes management, and noninvasive methods can be more convenient and less painful than traditional finger-prick methods.AimWe aim to report a noncontact speckle-based blood glucose measurement system that utilizes artificial intelligence (AI) data processing to improve glucose detection accuracy. The study also explores the influence of an alternating current (AC) induced magnetic field on the sensitivity and selectivity of blood glucose detection.ApproachThe proposed blood glucose sensor consists of a digital camera, an AC-generated magnetic field source, a laser illuminating the subject’s finger, and a computer. A magnetic field is applied to the finger, and a camera records the speckle patterns generated by the laser light reflected from the finger. The acquired video data are preprocessed for machine learning (ML) and deep neural networks (DNNs) to classify blood plasma glucose levels. The standard finger-prick method is used as a reference for blood glucose level classification.ResultsThe study found that the noncontact speckle-based blood glucose measurement system with AI data processing allows for the detection of blood plasma glucose levels with high accuracy. The ML approach gives better results than the tested DNNs as the proposed data preprocessing is highly selective and efficient.ConclusionsThe proposed noncontact blood glucose sensing mechanism utilizing AI data processing and a magnetic field can potentially improve glucose detection accuracy, making it more convenient and less painful for patients. The system also allows for inexpensive blood glucose sensing mechanisms and fast blood glucose screening. The results suggest that noninvasive methods can improve blood glucose detection accuracy, which can have significant implications for diabetes management. Investigations involving representative sampling data, including subjects of different ages, gender, race, and health status, could allow for further improvement.
Significance: The ability to perform frequent non-invasive monitoring of glucose in the bloodstream is very applicable for diabetic patients.Aim: We experimentally verified a non-invasive multimode fiber-based technique for sensing glucose concentration in the bloodstream by extracting and analyzing the collected speckle patterns.Approach: The proposed sensor consists of a laser source, digital camera, computer, multimode fiber, and alternating current (AC) generated magnetic field source. The experiments were performed using a covered (with cladding and jacket) and uncovered (without cladding and jacket) multimode fiber touching the skin under a magnetic field and without it. The subject’s finger was placed on a fiber to detect the glucose concentration. The method tracks variations in the speckle patterns due to light interaction with the bloodstream affected by blood glucose.Results: The uncovered fiber placed above the finger under the AC magnetic field (150 G) at 140 Hz was found to have a lock-in amplification role, improving the glucose detection precision. The application of the machine learning algorithms in preprocessed speckle pattern data increase glucose measurement accuracy. Classification of the speckle patterns for uncovered fiber under the AC magnetic field allowed for detection of the blood glucose with high accuracy for all tested subjects compared with other tested configurations.Conclusions: The proposed technique was theoretically analyzed and experimentally validated in this work. The results were verified by the traditional finger-prick method, which was also used for classification as a conventional reference marker of blood glucose levels. The main goal of the proposed technique was to develop a non-invasive, low-cost blood glucose sensor for easy use by humans.
Microseismic wave detection is important to avoid major disaster in coal mines. Here, a scheme of differential power measurement is proposed that can detect microseismic waves by converting minimal wavelength shift detected by a fiber Bragg grating interrogation system into corresponding variation in optical power. The Bragg-reflected signals are phase modulated by 500-MHz RF signal and detected by differential arrangement circuit consisting of photodetectors (PDs). The differential power at the PD is calculated theoretically and verified through simulation experiment. The variation of differential power with applied strain is nonlinear with the threshold at 100 με. The sensitivity of the present system is 0.041 dB / με below the threshold and increases to 0.598 dB / με above the threshold with the system resolution of 16.72 nε.
A highly sensitive and high resolution Interrogation setup for Fiber Bragg Grating (FBG) based sensing to measure low strain variation (i.e ~100με) effectively is being proposed in this manuscript. This system uses edge detection interrogation scheme using two optical signals generated through carrier compressed modulation scheme. Here, Dual Drive Mach-Zehnder Modulator (DD-MZM) is employed to generate carrier suppressed first order sidebands, which are then used as two optical signals and detected on two different power meters. Differential power measurement technique is used to calculate change in wavelength or applied strain at detector end. This system can provide system sensitivity as high as 0.3193 dBm.με-1 and resolution upto 31.31nε in term of strain or 37.2fm in terms of wavelength. Which is much higher than present commercially available interrogation system (~0.8με). The proposed interrogation system can be employed in biomedical sensing to monitor cardiac and respiratory activity even during Magnetic Resonance Imaging (MRI) scanning condition as they are not prone to any electromagnetic interference.
Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks.
You are receiving this notice because your organization may not have SPIE eBooks access.*
*Shibboleth/Open Athens users─please
sign in
to access your institution's subscriptions.
To obtain this item, you may purchase the complete book in print or electronic format on
SPIE.org.
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.