Dr. Antonio Lauto Profile

Dr. Antonio Lauto

Senior Lecturer at Western Sydney Univ

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Author

Publications (9)

Proceedings Article | 7 March 2019 Presentation + Paper

A genome-wide screen for tolerance to rose bengal photodynamic therapy and its use in onychomycosis treatment

J. Houang, G. Perrone, C. Pedrinazzi, L. Longo, D. Mawad, P. Boughton, A. Ruys, A. Lauto

Proceedings Volume 10863, 108630N (2019) https://doi.org/10.1117/12.2509284

KEYWORDS: Photodynamic therapy, Genetics, In vitro testing, Yeast, Laser irradiation, Fungi

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Proceedings Article | 4 March 2019 Presentation

Stimulation and repair of peripheral nerves using a bioadhesive graft-antenna (Conference Presentation)

Antonio Lauto, Ashour Sliow, Zhi Ma, Gaetano Gargiulo, David Mahns, Damia Mawad, Paul Breen, Marcus Stoodley, Jessica Houang, Giuseppe Tettamanzi, John Morley, Leonardo Longo, Rhiannon Kuchel

Proceedings Volume 10864, 1086405 (2019) https://doi.org/10.1117/12.2508255

KEYWORDS: Axons, Nerve, Antennas, Magnetism, Injuries, Bridges, Gold, Tissue optics, Action potentials

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Proceedings Article | 22 February 2006 Paper

Chitosan adhesive for laser tissue repair

A. Lauto, M. Stoodley, A. Avolio, L. Foster

Proceedings Volume 6078, 60780X (2006) https://doi.org/10.1117/12.645155

KEYWORDS: Adhesives, Tissues, Laser tissue interaction, Nerve, Intestine, Axons, Temperature metrology, Laser welding, In vivo imaging, Laser bonding

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Proceedings Article | 13 July 2004 Paper

Albumin-genipin solder for laser tissue welding

Antonio Lauto, John Foster, Albert Avolio, Laura Poole-Warren

Proceedings Volume 5312, (2004) https://doi.org/10.1117/12.531466

KEYWORDS: Tissues, Laser welding, Laser tissue interaction, Proteins, Solids, Intestine, Interfaces, Semiconductor lasers, Natural surfaces, In vivo imaging

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Proceedings Article | 12 December 2003 Paper

Low-temperature solder for laser tissue welding

Antonio Lauto, Robert Stewart, D. Felsen, John Foster, Laura Poole-Warren, Dix Poppas

Proceedings Volume 5287, (2003) https://doi.org/10.1117/12.544880

KEYWORDS: Tissues, Laser welding, Interfaces, Laser tissue interaction, Infrared radiation, Infrared imaging, Temperature metrology, Solids, Intestine, Natural surfaces

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Proceedings Article | 14 January 1998 Paper

Laser solder repair technique for nerve anastomosis: temperatures required for optimal tensile strength

Karen McNally-Heintzelman, Judith Dawes, Antonio Lauto, Anthony Parker, Earl Owen, James Piper

Proceedings Volume 3195, (1998) https://doi.org/10.1117/12.297913

KEYWORDS: Nerve, Laser welding, Proteins, Solids, Semiconductor lasers, Laser tissue interaction, Temperature metrology, Interfaces, Tissues, Radiometry

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Laser-assisted repair of nerves is often unsatisfactory and has a high failure rate. Two disadvantages of laser assisted procedures are low initial strength of the resulting anastomosis and thermal damage of tissue by laser heating. Temporary or permanent stay sutures are used and fluid solders have been proposed to increase the strength of the repair. These techniques, however, have their own disadvantages including foreign body reaction and difficulty of application. To address these problems solid protein solder strips have been developed for use in conjunction with a diode laser for nerve anastomosis. The protein helps to supplement the bond, especially in the acute healing phase up to five days post- operative. Indocyanine green dye is added to the protein solder to absorb a laser wavelength (approximately 800 nm) that is poorly absorbed by water and other bodily tissues. This reduces the collateral thermal damage typically associated with other laser techniques. An investigation of the feasibility of the laser-solder repair technique in terms of required laser irradiance, tensile strength of the repair, and solder and tissue temperature is reported here. The tensile strength of repaired nerves rose steadily with laser irradiance reaching a maximum of 105 plus or minus 10 N.cm^-2 at 12.7 W.cm^-2. When higher laser irradiances were used the tensile strength of the resulting bonds dropped. Histopathological analysis of the laser- soldered nerves, conducted immediately after surgery, showed the solder to have adhered well to the perineurial membrane, with minimal damage to the inner axons of the nerve. The maximum temperature reached at the solder surface and at the solder/nerve interface, measured using a non-contact fiber optic radiometer and thermocouple respectively, also rose steadily with laser irradiance. At 12.7 W.cm^-2, the temperatures reached at the surface and at the interface were 85 plus or minus 4 and 68 plus or minus 4 degrees Celsius respectively. This study demonstrates the feasibility of the laser-solder repair technique for nerve anastomosis resulting in improved tensile strength. The welding temperature required to achieve optimal tensile strength has been identified.

Proceedings Article | 15 May 1997 Paper

Laser-activated solder weld repair of the inferior alveolar nerve in rats

Nigel Curtis, Antonio Lauto, Rodney Trickett, Earl Owen, D. Walker

Proceedings Volume 2973, (1997) https://doi.org/10.1117/12.273589

KEYWORDS: Nerve, Laser welding, Neurons, Axons, Control systems, Semiconductor lasers, Beam controllers, Bone, Infrared lasers, Infrared radiation

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Proceedings Article | 19 January 1996 Paper

Laser-activated protein bands for peripheral nerve repair

Antonio Lauto, Rodney Trickett, Richard Malik, Judith Dawes, Earl Owen

Proceedings Volume 2623, (1996) https://doi.org/10.1117/12.230350

KEYWORDS: Nerve, Laser welding, Proteins, Axons, Semiconductor lasers, Laser tissue interaction, Surgery, In vivo imaging, Action potentials, Electrodes

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Proceedings Article | 12 May 1995 Paper

Laser-activated protein solder for peripheral nerve repair

Rodney Trickett, Antonio Lauto, Judith Dawes, Earl Owen

Proceedings Volume 2395, (1995) https://doi.org/10.1117/12.209075

KEYWORDS: Nerve, Laser welding, Proteins, Semiconductor lasers, Surgery, Laser vision correction, Laser therapeutics, Action potentials, Laser tissue interaction, Electrodes

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