Dr. Catherine A. Kendall Profile

Dr. Catherine A. Kendall

Principal Clinical Scientist at Gloucestershire Hospitals NHS Foundation Trust

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Author

Publications (23)

Proceedings Article | 7 March 2016 Paper

Evaluation of a multi-fibre needle Raman probe for tissue analysis

Leanne Fullwood, Ingeborg Iping Petterson, Alexander Dudgeon, Gavin Lloyd, Catherine Kendall, Charlie Hall, John C. Day, Nick Stone

Proceedings Volume 9704, 97040G (2016) https://doi.org/10.1117/12.2230005

KEYWORDS: Raman spectroscopy, Tissues, Lymphatic system, Cancer, Spectroscopy, Fiber optics, Tissue optics, Optical fibers, Light scattering, Surgery, Diagnostics, In vivo imaging, Biopsy, Visualization, Bone

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Proceedings Article | 7 March 2016 Presentation + Paper

Identification of GI cancers utilising rapid mid-infrared spectral imaging

Jayakrupakar Nallala, Gavin Lloyd, Catherine Kendall, Hugh Barr, Neil Shepherd, Nick Stone

Proceedings Volume 9703, 970303 (2016) https://doi.org/10.1117/12.2209363

KEYWORDS: Cancer, Mid-IR, Imaging spectroscopy, Tissues, Tumors, Infrared imaging, Pathology, FT-IR spectroscopy, Statistical modeling, Statistical analysis

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Proceedings Article | 7 March 2016 Presentation + Paper

The road map towards providing a robust Raman spectroscopy-based cancer diagnostic platform and integration into clinic

Katherine Lau, Martin Isabelle, Gavin Lloyd, Oliver Old, Neil Shepherd, Ian Bell, Jennifer Dorney, Aaran Lewis, Riana Gaifulina, Manuel Rodriguez-Justo, Catherine Kendall, Nicolas Stone, Geraint Thomas, David Reece

Proceedings Volume 9704, 97040B (2016) https://doi.org/10.1117/12.2230007

KEYWORDS: Raman spectroscopy, Cancer, Data modeling, Diagnostics, Tissues, Pathology, Tissue optics, Statistical modeling, Remote sensing, Tumor growth modeling

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SPIE Journal Paper | 3 September 2012 Open Access

Assessment of a custom-built Raman spectroscopic probe for diagnosis of early oesophageal neoplasia

L. Max Almond, Joanne Hutchings, Catherine Kendall, Gavin Lloyd, John Day, Oliver Stevens, Neil Shepherd, Hugh Barr, Nicholas Stone

JBO, Vol. 17, Issue 8, 081421, (September 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.8.081421

KEYWORDS: Raman spectroscopy, Endoscopy, Tissues, Biopsy, Diagnostics, Spectroscopy, Tissue optics, Remote sensing, In vivo imaging, Cancer

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Proceedings Article | 1 February 2012 Paper

Assessing the performance of spectroscopic models for cancer diagnostics using cross-validation and permutation testing

G. Lloyd, J. Hutchings, L. Almond, H. Barr, C. Kendall, N. Stone

Proceedings Volume 8219, 82190C (2012) https://doi.org/10.1117/12.919864

KEYWORDS: Computer simulations, Raman spectroscopy, Spectroscopy, Cancer, Tumor growth modeling, Diagnostics, Surface plasmons, Statistical modeling, Performance modeling, Spectroscopes

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Proceedings Article | 1 February 2012 Paper

Preclinical evaluation of a Raman spectroscopic probe for endoscopic classification of oesophageal pathologies

L. M. Almond, J. Hutchings, G. Lloyd, J. Francis-Jones, N. Stone, H. Barr, C. Kendall

Proceedings Volume 8219, 82190L (2012) https://doi.org/10.1117/12.919876

KEYWORDS: Raman spectroscopy, Endoscopy, Tissue optics, Spectroscopy, Remote sensing, Pathology, Imaging systems, Tissues, Cancer, Prototyping

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Proceedings Article | 9 June 2011 Paper

Infrared spectroscopy to estimate the gross biochemistry associated with different colorectal pathologies

J. Wood, C. Kendall, G. LLoyd, N. Shepherd, T. Cook, N. Stone

Proceedings Volume 8087, 80870P (2011) https://doi.org/10.1117/12.889605

KEYWORDS: Tissues, FT-IR spectroscopy, Cancer, Infrared spectroscopy, Pathology, Biological research, Colorectal cancer, Biopsy, Colon, Tissue optics

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SPIE Journal Paper | 1 November 2010 Open Access

Evaluation of linear discriminant analysis for automated Raman histological mapping of esophageal high-grade dysplasia

Joanne Hutchings, Catherine Kendall, Neil Shepherd, Hugh Barr, Nicholas Stone

JBO, Vol. 15, Issue 06, 066015, (November 2010) https://doi.org/10.1117/12.10.1117/1.3512244

KEYWORDS: Raman spectroscopy, Tissues, Pathology, Data modeling, Associative arrays, Spatial resolution, Statistical modeling, Biological research, Tissue optics, Performance modeling

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Proceedings Article | 12 February 2010 Paper

Ultra-low spatial resolution Raman mapping using a novel fibre optic probe

J. Hutchings, C. Kendall, N. Shepherd, H. Barr, J. Day, N. Stone

Proceedings Volume 7560, 75600N (2010) https://doi.org/10.1117/12.858803

KEYWORDS: Raman spectroscopy, Tissues, Pathology, Biopsy, In vivo imaging, Cancer, Luminescence, Fiber optics, Principal component analysis, Spatial resolution

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Proceedings Article | 8 February 2008 Paper

Rapid Raman microscopic imaging for potential histological screening

Joanne Hutchings, Catherine Kendall, Neil Shepherd, Hugh Barr, Brian Smith, Nicholas Stone

Proceedings Volume 6853, 685305 (2008) https://doi.org/10.1117/12.786440

KEYWORDS: Raman spectroscopy, Signal to noise ratio, Associative arrays, Tissues, Biopsy, Charge-coupled devices, Connective tissue, Brain mapping, Pathology, Cancer

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Proceedings Article | 27 February 2006 Paper

Infrared spectroscopy: a novel tool to aid classification of DCIS

K. Subramanian, N. Stone, C. Kendall, J. C. Brown, K. McCarthy, J. Bristol, Y. H. Chan

Proceedings Volume 6093, 60930J (2006) https://doi.org/10.1117/12.644512

KEYWORDS: Infrared spectroscopy, Tissues, Absorption, Infrared radiation, Tumor growth modeling, Tissue optics, Breast, Pathology, Proteins, Statistical analysis

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Proceedings Article | 27 February 2006 Paper

Raman spectroscopic biochemical mapping of tissues

Nicholas Stone, Maria Hart Prieto, Catherine Kendall, Geeta Shetty, Hugh Barr

Proceedings Volume 6093, 60930U (2006) https://doi.org/10.1117/12.644178

KEYWORDS: Tissues, Raman spectroscopy, Pathology, Spectroscopy, Collagen, Cancer, Biological research, Imaging spectroscopy, Visualization, Bladder

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Proceedings Article | 21 February 2006 Paper

Raman spectroscopic analysis of atypical proliferative lesions of the breast

K. Subramanian, C. Kendall, N. Stone, J. Brown, K. McCarthy, J. Bristol, Y. Chan

Proceedings Volume 6088, 60880B (2006) https://doi.org/10.1117/12.644553

KEYWORDS: Breast, Raman spectroscopy, Pathology, Breast cancer, Tissues, Chemical analysis, Cancer, Principal component analysis, Tumor growth modeling, Spectroscopy

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Atypical lesions of the breast have potential to turn malignant. The diagnosis of these lesions has increased considerably with screening mammography. A good understanding of their progression to invasive cancer is yet to be proved. Using Raman spectroscopy to study their chemical finger printing at different stages of proliferation a clear picture of whether a progression exists between lesions could be made. At present there is no clear recognition of the biochemical changes that distinguish between the different proliferative lesions of the breast. Our aim is to understand these changes through Raman mapping studies. Raman spectroscopy is a highly sensitive and specific technique for demonstration of biochemical changes in different atypical proliferative lesions of the breast. The technique could be used to classify the different grades and analyse progression of pathology in the proliferative lesions of the breast. Breast pathologists carefully marked 50 ducts and classified the different pathology on H and E sections from biopsy samples. Raman spectra were measured, using a Renishaw Raman Spectrometer, on a 20-micron thick consecutive frozen section. Principal component analysis was undertaken using Matlab. Pseudocolor maps of the principal components scores have been generated. The peaks of the corresponding loads were identified enabling visualisation of the biochemical changes associated with proliferative lesions. Proliferative lesions of the duct were grouped according to the existing standard pathological classification and formed four major groups-HUT, ADH, DCIS and IDC. Spectra of biochemical constituents were fitted to mean spectra from selected regions, taken from maps of each pathology, to identify the relative concentration of the constituents. The study gave an insight into chemical make up of the ducts in each pathology group and showed similar results to earlier studies in progression but no clear-cut demarcation or continuum of the proliferative disease.

Proceedings Article | 8 October 2005 Paper

Raman spectroscopy is sensitive and specific in the detection of lymph node metastases in breast cancer

Jenny Smith, Catherine Kendall, Alastair Sammon, Jonathan Christie-Brown, Trupti Mandalia, Nicholas Stone

Proceedings Volume 5862, 586202 (2005) https://doi.org/10.1117/12.633004

KEYWORDS: Lymphatic system, Raman spectroscopy, Breast cancer, Tumor growth modeling, Tissues, Collagen, Biochemistry, Imaging spectroscopy, Spectroscopy, Tissue optics

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Proceedings Article | 1 July 2004 Paper

Urological applications of Raman spectroscopy for improved malignant diagnostics

M. Consuelo Hart Prieto, Paul Crow, Catherine Kendall, Jeremy Uff, Mark Wright, Alistair Ritchie, Nicholas Stone

Proceedings Volume 5321, (2004) https://doi.org/10.1117/12.528907

KEYWORDS: Tumor growth modeling, Raman spectroscopy, Prostate, Bladder, Biopsy, Cancer, Data modeling, Bladder cancer, Pathology, Diagnostics

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Proceedings Article | 9 October 2003 Paper

Multiphoton imaging in the detection of malignancy in the oesophagus

Catherine Kendall, Karen McCloskey, Nicholas Stone, Hugh Barr, Douglas Greenhalgh

Proceedings Volume 5139, (2003) https://doi.org/10.1117/12.500486

KEYWORDS: Collagen, Tissues, Tissue optics, Luminescence, Biomedical optics, Visualization, Cancer, Biopsy, Microscopes, Imaging systems

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Proceedings Article | 8 October 2003 Paper

Raman spectroscopy in the assessment of breast cancer and axillary lymph node metastases

Jenny Smith, Catherine Kendall, Jay Christie-Brown, Alastair Sammon, Nicholas Stone

Proceedings Volume 5141, (2003) https://doi.org/10.1117/12.500472

KEYWORDS: Raman spectroscopy, Lymphatic system, Breast, Tissues, Breast cancer, Diagnostics, Tumor growth modeling, Tissue optics, Pathology, Principal component analysis

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Proceedings Article | 8 October 2003 Paper

Raman spectral mapping for the illumination of biochemical changes associated with malignancy in the oesophagus

Catherine Kendall, Nicholas Stone, Neil Shepherd, Hugh Barr

Proceedings Volume 5141, (2003) https://doi.org/10.1117/12.500438

KEYWORDS: Proteins, Raman spectroscopy, Tissue optics, Tissues, Spectroscopy, Biological research, Pathology, Optical spectroscopy, Statistical analysis, Surgery

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Proceedings Article | 27 March 2002 Paper

Optimum procedure for construction of spectral classification algorithms for medical diagnosis

Catherine Kendall, Hugh Barr, Neil Shepherd, Nicholas Stone

Proceedings Volume 4614, (2002) https://doi.org/10.1117/12.460791

KEYWORDS: Pathology, Statistical modeling, Gold, Raman spectroscopy, Tumor growth modeling, Spectroscopy, Cancer, Tissues, Biopsy, Diagnostics

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Proceedings Article | 27 March 2002 Paper

Near-infrared Raman spectroscopy for detection and classification of gastrointestinal disease

Nicholas Stone, Catherine Kendall, Nitya Chandratreya, Neil Shepherd, Hugh Barr

Proceedings Volume 4614, (2002) https://doi.org/10.1117/12.460788

KEYWORDS: Raman spectroscopy, Pathology, Tissues, Biopsy, Colon, Spectroscopy, Statistical analysis, Cancer, Statistical modeling, Data modeling

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Proceedings Article | 16 November 2000 Paper

Raman spectroscopy for the diagnosis of dysplasia in columnar and squamous epithelium

Catherine Kendall, Tom Bakker Schut, Nicholas Stone, Pela Stravroulaki, Gerwin Puppels, Hugh Barr

Proceedings Volume 4161, (2000) https://doi.org/10.1117/12.409321

KEYWORDS: Raman spectroscopy, Tissues, Cancer, Pathology, Biopsy, Tissue optics, Spectroscopy, Statistical analysis, In vivo imaging, In vitro testing

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Proceedings Article | 8 May 2000 Paper

Progress in the detection of neoplastic progress and cancer by Raman spectroscopy

Tom Bakker Schut, Nicholas Stone, Catherine Kendall, Hugh Barr, Hajo Bruining, Gerwin Puppels

Proceedings Volume 3918, (2000) https://doi.org/10.1117/12.384932

KEYWORDS: Raman spectroscopy, Tissues, Tissue optics, Biopsy, Data modeling, Cancer, Statistical modeling, Tumor growth modeling, Spectroscopy, Pathology

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Proceedings Article | 8 May 2000 Paper

Raman spectroscopy: a diagnostic tool for detection of early malignant changes in the larynx

Nicholas Stone, Pelagia Stavroulaki, Catherine Kendall, Martin Birchall, Hugh Barr

Proceedings Volume 3918, (2000) https://doi.org/10.1117/12.384933

KEYWORDS: Raman spectroscopy, Tissues, Pathology, Diagnostics, Biopsy, Statistical analysis, Cancer, Near infrared, Biological research, Tissue optics

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Showing 5 of 23 publications

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