In the development of microfluidic systems, conventional 2D processing technologies are increasingly difficult to meet the requirement of integration of multifunctional components within a microchannel. Recently, two-photon polymerization (TPP) technology has emerged as a novel alternative to fabricate 3D microdevices functionalizing conventional microfluidic chips. Here, the development of TPP microfluidic technology comprising parallel fabrication, holographic patterning method and real-time lithography in a controlled flow is reported. And a series of functional microcomponents containing microfilters, microsorters, microtrap, tunable microlens are fabricated by above methods. The results indicate that the processing of microfluidic devices is simple, timesaving, low cost and programmable designability. The functional microchips are further used in blood cells sorting, biomedical sensing, microparticle purification and trapping with successful test results.
Recently, annular beams have been developed to rapidly fabricate microscope tubular structures via two-photon polymerization, but the distribution of the light field is limited to a ring pattern. Here a Fresnel lens is designed and applied to modulate the light field into a uniform quadrangle or hexagon shape with controllable diameters. By applying a spatial light modulator to load the phase information of the Fresnel lens, quadrangle and hexagon structures are achieved through single exposure of a femtosecond laser. A 3×6 array of structures is made within 9 s. Comparing with the conventional holographic processing, this method shows higher uniformity, high efficiency, better flexibility, and easy operation. The approach exhibited a promising prospect in rapidly fabricating structures such as tissue engineering scaffolds and variously shaped tubular arrays.
A method for holographic femtosecond laser parallel processing is proposed, which can suppress the interference of zero-order light effectively and improve the energy utilization rate. In order to blaze the target pattern to the peak position of zero-order interference, a phase-only hologram containing a digital blazed grating is designed and generated, and the energy of the target pattern can be increased by 3.793 times in theory. In addition, by subsequently increasing the phase of the divergent spherical wave, the focal plane of the target pattern and the plane of the multiorder diffraction beam resulting from the pixelated structure of the spatial light modulator (SLM) can be separated. Both a high-pass filter and aperture are used to simultaneously eliminate the influences of zero-order light and multiorder interferential patterns. A system based on the phase-only SLM (with resolution of 1920×1080) is set up to validate the proposed method. The experimental results indicate that the proposed method can achieve high-quality holographic femtosecond laser parallel processing with a significantly improved energy utilization rate.
A novel method for holographic femtosecond laser parallel processing is proposed, which can suppress the interference
of zero order light effectively and improve the energy utilization rate. In order to blaze the target pattern to the peak
position of zero-order interference, a phase-only hologram containing digital blazed grating are designed and generated,
The energy of the target pattern can be increased to 5.297 times in theory. In addition, by subsequently increasing the
phase of divergent spherical wave, the focal plane of the target pattern and the plane of multi-order diffraction beam
resulted from pixelated structure of the spatial light modulator (SLM) can be separated. Both the high pass filter and
aperture are used to eliminate the influences of zero-order light and multi-order interferential patterns simultaneously. A
system based on the phase-only SLM (with resolution of 1920*1080) is set up to validate the proposed method. The
experimental results indicate that the proposed method can achieve high quality holographic femtosecond laser parallel
processing with a significantly improved energy utilization rate.
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