Mr. Chenxu Li Profile

Chenxu Li

at State Key Lab of Modern Optical Instrumentation

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Proceedings Article | 7 April 2023 Poster + Paper

Low-dose dual-tracer PET image reconstruction based on attention mechanism

Fuzhen Zeng, Chenxu Li, Jingwan Fang, Huafeng Liu

Proceedings Volume 12463, 124632D (2023) https://doi.org/10.1117/12.2653365

KEYWORDS: Positron emission tomography, Image restoration, Reconstruction algorithms, Image processing, Image quality

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Since the multi-tracer positron emission tomography (PET) technology will increase the total dose of tracers, it is necessary to study the low-dose multi-tracer PET technology. In this paper, we proposed a model based on attention mechanism to estimate the standard-dose single-tracer sinogram from the low-dose dual-tracer sinogram, that is, to achieve both standard-dose estimation and dual-tracer signal separation in sinogram domain. Both the spatial attention and channel attention were implemented. We cascaded the FBP-Net for reconstruction after the proposed model, and verified the proposed method in simulation experiment and rat experiment. At the same time, we compared the results of dual-tracer PET signal separation in sinogram domain and activity map domain. The results prove the effectiveness of the proposed method in the problem of low-dose dual-tracer PET image reconstruction, and also show that signal separation in sinogram domain is more effective than separation in activity map domain.

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