Dr. Christian T. A. Brown Profile

Dr. Christian T. A. Brown

SUPA Lecturer/Biophotonics at Univ of St Andrews

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Author

Publications (20)

SPIE Journal Paper | 6 February 2024 Open Access

Simulating photodynamic therapy for the treatment of glioblastoma using Monte Carlo radiative transport

Louise Finlayson, Lewis McMillan, Szabolcs Suveges, Douglas Steele, Raluca Eftimie, Dumitru Trucu, Christian Thomas A. Brown, Ewan Eadie, Kismet Hossain-Ibrahim, Kenneth Wood

JBO, Vol. 29, Issue 02, 025001, (February 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.2.025001

KEYWORDS: Photodynamic therapy, Oxygen, Tumors, Monte Carlo methods, Resection, Tissues, Brain tissue, Brain, Light sources, Voxels

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Proceedings Article | 7 December 2021 Paper

Laser assisted restorative mineralization of dental enamel

Antonios Anastasiou, Emaan Alshubhe, Vasiliki Panagiotopoulou, Simon Strafford, Tom Edward, C. T. Brown, Animesh Jha

Proceedings Volume 11919, 1191906 (2021) https://doi.org/10.1117/12.2614446

KEYWORDS: Tissues, Minerals, Coating, Calcium, Natural surfaces, Pulsed laser operation, Laser systems engineering, Laser sintering, Laser dentistry, Femtosecond phenomena

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SPIE Journal Paper | 7 September 2021 Open Access

Imaging in thick samples, a phased Monte Carlo radiation transfer algorithm

Lewis McMillan, Sascha Reidt, Cameron McNicol, Isla R. Barnard, Michael MacDonald, Christian T. Brown, Kenneth Wood

JBO, Vol. 26, Issue 09, 096004, (September 2021) https://doi.org/10.1117/12.10.1117/1.JBO.26.9.096004

KEYWORDS: Monte Carlo methods, Bessel beams, Gaussian beams, Scattering, Laser scattering, Photons, Sensors, Axicons, Tissues, Computer simulations

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Proceedings Article | 17 May 2018 Presentation + Paper

Towards high-power on-chip GHz frequency combs

A. Choudhary, A. Lagatsky, P. Kannan, C. T. Brown, D. Shepherd

Proceedings Volume 10683, 106830W (2018) https://doi.org/10.1117/12.2306711

KEYWORDS: Waveguides, Frequency combs, Mode locking, Dispersion, Waveguide lasers, Optical amplifiers, Glasses, Telecommunications, Quadrature amplitude modulation, Mirrors

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Proceedings Article | 29 February 2016 Presentation + Paper

New insights into photodynamic therapy treatment through the use of 3D Monte Carlo radiation transfer modelling

C. Campbell, Kenneth Wood, C. Tom Brown, Harry Moseley

Proceedings Volume 9689, 96890Q (2016) https://doi.org/10.1117/12.2212240

KEYWORDS: Photodynamic therapy, Monte Carlo methods, 3D modeling, Tissue optics, Absorption, Fractal analysis, Tissues, Photons, Skin, Tumor growth modeling

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Proceedings Article | 19 June 2015 Paper

3D Monte Carlo radiation transfer modelling of photodynamic therapy

C. Louise Campbell, Craig Christison, C. Tom Brown, Kenneth Wood, Ronan Valentine, Harry Moseley

Proceedings Volume 9531, 95311H (2015) https://doi.org/10.1117/12.2180744

KEYWORDS: Skin, Photodynamic therapy, Light sources, Tissue optics, Absorption, Optical properties, Scattering, Monte Carlo methods, 3D modeling, Modeling

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Proceedings Article | 28 February 2014 Paper

Near- infrared, mode-locked waveguide lasers with multi-GHz repetition rates

A. Choudhary, A. Lagatsky, Z. Zhang, K. Zhou, Q. Wang, R. Hogg, K. Pradeesh, E. Rafailov, B. Resan, A. E. Oehler, K. Weingarten, W. Sibbett, C. T. Brown, D. Shepherd

Proceedings Volume 8959, 895913 (2014) https://doi.org/10.1117/12.2035639

KEYWORDS: Glasses, Mode locking, Waveguide lasers, Waveguides, Dispersion, Picosecond phenomena, Quantum dots, Mirrors, Solitons, Interferometers

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Proceedings Article | 15 May 2012 Paper

Optically-induced switching between mode-locked and unmode-locked continuous wave regimes of a femtosecond Cr4+:forsterite laser

D. Walsh, C. Crombie, W. Sibbett, C. T. Brown, V. Savitski, D. Burns, S. Calvez

Proceedings Volume 8433, 84330G (2012) https://doi.org/10.1117/12.922340

KEYWORDS: Mode locking, Switching, Absorption, Continuous wave operation, Optical pumping, Semiconductor lasers, Quantum wells, Pulsed laser operation, Saturable absorption, Optical tweezers

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SPIE Journal Paper | 15 May 2012 Open Access

Tissue surface as the reference arm in Fourier domain optical coherence tomography

Nikola Krstajic, Christian Brown, Kishan Dholakia, Mario Giardini

JBO, Vol. 17, Issue 7, 071305, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.7.071305

KEYWORDS: Optical coherence tomography, Natural surfaces, Skin, Tissues, Tissue optics, Charge-coupled devices, Reflectivity, Reflection, Image processing, Aluminum

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SPIE Journal Paper | 1 April 2011 Open Access

Monte Carlo modeling of in vivo protoporphyrin IX fluorescence and singlet oxygen production during photodynamic therapy for patients presenting with superficial basal cell carcinomas

Ronan Valentine, Christian Brown, Kenneth Wood, Harry Moseley, Sally Ibbotson

JBO, Vol. 16, Issue 04, 048002, (April 2011) https://doi.org/10.1117/12.10.1117/1.3562540

KEYWORDS: Luminescence, Tumors, Photodynamic therapy, Monte Carlo methods, Oxygen, Tissue optics, In vivo imaging, Optical properties, Tumor growth modeling, Fluorescence spectroscopy

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Proceedings Article | 28 February 2009 Paper

GaInNAs semiconductor disk lasers as pump sources for Tm3+(,Ho3+)-doped glass, crystal and fibre lasers

Sharon Vetter, L. McKnight, Stephane Calvez, Martin Dawson, F. Fusari, Alexander Lagatsky, Wilson Sibbett, Christian Brown, Ville-Markus Korpijärvi, Mircea Guina, B. Richards, G. Jose, Animesh Jha

Proceedings Volume 7193, 719317 (2009) https://doi.org/10.1117/12.811116

KEYWORDS: Glasses, Laser crystals, Crystals, Semiconductor lasers, Fiber lasers, Laser glasses, Wavelength tuning, Mirrors, Semiconductors, Disk lasers

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Proceedings Article | 20 February 2008 Paper

Femtosecond cellular transfection using a non-diffracting beam

X. Tsampoula, V. Garcés-Chávez, M. Comrie, D. Stevenson, B. Agate, C. T. Brown, F. Gunn-Moore, K. Dholakia

Proceedings Volume 6854, 68541L (2008) https://doi.org/10.1117/12.762677

KEYWORDS: Bessel beams, Gaussian beams, Femtosecond phenomena, Axicons, Beam propagation method, Tissues, Nondiffracting beams, Fluorescent proteins, Biomedical optics, Genetics

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Proceedings Article | 14 February 2008 Paper

High-power Kerr-lens mode-locked ytterbium lasers

F. Bain, A. Lagatsky, C. T. Brown, W. Sibbett

Proceedings Volume 6871, 68712L (2008) https://doi.org/10.1117/12.762933

KEYWORDS: Mode locking, Semiconductor lasers, Crystals, Pulsed laser operation, Refractive index, Laser crystals, Femtosecond phenomena, Absorption, High power lasers, Polarization

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Proceedings Article | 23 August 2007 Paper

Advances in femtosecond lasers having enhanced efficiencies

A. Lagatsky, V. Kisel, F. Bain, C. T. A. Brown, N. V. Kuleshov, W. Sibbett

Proceedings Volume 6731, 67310E (2007) https://doi.org/10.1117/12.751894

KEYWORDS: Mode locking, Femtosecond phenomena, Crystals, Semiconductor lasers, Nonlinear crystals, Pulsed laser operation, Laser crystals, Mirrors, Solid state lasers, Second-harmonic generation

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Proceedings Article | 11 September 2006 Paper

Enhanced particle guiding using supercontinuum radiation

Pascal Fischer, Antonia Carruthers, Karen Volke-Sepulveda, Ewan Wright, Helen Little, Christian T. Brown, Wilson Sibbett, Kishan Dholakia

Proceedings Volume 6326, 63261G (2006) https://doi.org/10.1117/12.678080

KEYWORDS: Particles, Femtosecond phenomena, Optical spheres, Continuous wave operation, Chromatic aberrations, Bessel beams, Light scattering, Wave propagation, Absorption, Gaussian beams

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Proceedings Article | 17 April 2006 Paper

Compact and efficient femtosecond lasers

Tom Brown, Alexander Lagatsky, C. Leburn, Alan McWilliam, Abdul Sarmani, Maria Ana Cataluna, Ben Agate, Kishan Dholakia, David Stevenson, Wilson Sibbett, Yewjun Chai, Pisu Jiang, Kim Tan, Richard Penty, Ian White, Edik Rafailov, N. Kuleshov

Proceedings Volume 6190, 61900S (2006) https://doi.org/10.1117/12.668259

KEYWORDS: Femtosecond phenomena, Semiconductor lasers, Crystals, Pulsed laser operation, Laser crystals, Mode locking, Mirrors, Semiconductors, Laser development, Ultrafast phenomena

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Proceedings Article | 14 April 2006 Paper

Optical transfection of mammalian cells

David Stevenson, Ben Agate, Lynn Paterson, Tanya Lake, Muriel Comrie, Tom Brown, Andrew Riches, Peter Bryant, Wilson Sibbett, Frank Gunn-Moore, Kishan Dholakia

Proceedings Volume 6191, 61910D (2006) https://doi.org/10.1117/12.662325

KEYWORDS: Green fluorescent protein, Femtosecond phenomena, Titanium, Sapphire lasers, Biomedical optics, Microelectromechanical systems, Fluorescence correlation spectroscopy, Natural surfaces, Medical research, Cell biology

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Proceedings Article | 18 October 2004 Paper

Optical guiding with continuous wave and femtosecond lasers

Helen Little, C. T. Brown, Veneranda Garces-Chavez, Wilson Sibbett, Kishan Dholakia

Proceedings Volume 5514, (2004) https://doi.org/10.1117/12.560591

KEYWORDS: Particles, Continuous wave operation, Bessel beams, Femtosecond phenomena, Optical spheres, Polymers, Ferroelectric materials, Pulsed laser operation, Harmonic generation

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Proceedings Article | 1 September 2004 Paper

Diode-pumped femtosecond Yb:KYW laser with compact three-element cavity

Alexander Lagatsky, Christopher Leburn, Tom Brown, Wilson Sibbett

Proceedings Volume 5460, (2004) https://doi.org/10.1117/12.545653

KEYWORDS: Crystals, Semiconductor lasers, Mode locking, Femtosecond phenomena, Laser crystals, Continuous wave operation, Mirrors, Pulsed laser operation, Prisms, Output couplers

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Proceedings Article | 7 April 2004 Paper

Femtosecond Yb:KYW laser pumped by a single narrow-stripe laser diode

Alexander Lagatsky, Edward Rafailov, Christopher Leburn, Christian Brown, Ning Xiang, Oleg Okhotnikov, Wilson Sibbett

Proceedings Volume 5478, (2004) https://doi.org/10.1117/12.558357

KEYWORDS: Semiconductor lasers, Femtosecond phenomena, Mode locking, Laser damage threshold, Indium gallium arsenide, Semiconductors, Mirrors

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