Prof. Christoph Rau Profile

Prof. Christoph Rau

Beamline Scientist at Diamond Light Source Ltd

SPIE Involvement:

Author

Publications (31)

Proceedings Article | 7 November 2024 Presentation + Paper

Presentation + Paper

Hierarchical and operando tomography with x-rays and beyond

Christoph Rau, Darren Batey, Shashi Marathe, Leonard Turpin, Kudakwashe Jakata, Silvia Cipiccia, Isabel Antony, Roberto Volpe, Claus-Peter Richter, Alessandra Carriero, Maud Dumoux, Jürgen Schneider, Erica Dall'Armellina, Marc Holderied, Jan Van den Bulcke

Proceedings Volume 13152, 131521C (2024) https://doi.org/10.1117/12.3033126

KEYWORDS: Bone, Diamond, X-rays, Tomography, Porosity, Phase contrast, Coherence imaging, Cardiovascular disorders, Particles, Heart

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Proceedings Article | 6 October 2023 Presentation

Presentation

OCTOPI: Upgrade of the I13L beamline at Diamond Light Source Ltd.

Christoph Rau

Proceedings Volume PC12698, PC126980A (2023) https://doi.org/10.1117/12.2681913

KEYWORDS: Light sources, Diamond, Tomography, Synchrotron radiation, Data acquisition, Tunable filters, Temporal resolution, Spatial resolution, Optical filters, Monochromators

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The OCTOPI (Operando Computed TOmographic & Ptychographic Imaging) upgrade of the I13L beamline will occur as one of the selected (flagship) projects at Diamond Light Source, UK. The beamline I13L is dedicated to multi-scale, operando and high-throughput imaging. Two independent branchlines cover the micron to nano-resolution range, operating in the energy of 6-30keV. For operando imaging comparable recording times across the different length scales is important for studies under similar experimental conditions in terms of temporal resolution or number of specimen measured. Progress in throughput and data acquisition speed is achieved in different ways. A sample throughput of up to 300 samples a day is achieved for micro-tomography, using an automated sample changer. For imaging with grating interferometry and the full-field microscope, broadband radiation of the undulator source can be used. The bandpass is selected either with a multilayer monochromator or with filters and a mirror. Highest spatial resolution is achieved with ptychography, acquiring data with 10kHz speed and recording tomographic data sets within few hours. Across the different length scales, the gap between the recording times will be significantly reduced and permit multi-scale imaging on a similar number of specimen and time scales. We will discuss the aims of the upgrade and the science to be addressed. The design and layout options for the upgrade will be discussed. References: - M. Storm, F. Döring, S. Marathe, S. Cipiccia, C. David, C. Rau, Journal Of Synchrotron Radiation 29 (2021) 10.1107/S1600577521011206. - S. Marathe, R. F. Ziesche, G. Das, S. L. M. Schroeder, E. Baird, C. Rau, , in Proceedings of SPIE 2021, 11840, (2021) pp. 11840 10.1117/12.2598481. - S. Cipiccia, D. Batey, X. Shi, S. Williams, K. Wanelik, A. Wilson, P. Martin, T. Scott and C. Rau, in 13th International Conference on Synchrotron Radiation Instrumentation, 2019, AIP Conference Proceedings, edited by, S. Gwo, et al., 2054, (2019), pp. 050005. - D. Batey, C. Rau, S. Cipiccia, Scientific Reports 12, 10.1038/s41598-022-11292-8

Proceedings Article | 10 April 2023 Presentation + Paper

Presentation + Paper

Advanced x-ray imaging techniques in tissue engineering: a new construct assessment platform for enabling the regeneration of personalised organs

Savvas Savvidis, Mattia F. Gerli, Antonio Citro, Lorenzo Massimi, Charlotte Hagen, Marco Endrizzi, Alessia Atzeni, Alberto Astolfo, Michela Esposito, Olumide Ogunbiyi, Mark Turmaine, Elizabeth Smith, Silvia Cipiccia, Christoph Rau, Peng Li, Roberto Lutman, Giulia Selmin, Natalie Durkin, Soichi Shibuya, Marianna Scuglia, Marco Pellegrini, Paolo De Coppi, Alessandro Olivo

Proceedings Volume 12468, 124680R (2023) https://doi.org/10.1117/12.2653075

KEYWORDS: Visualization, Tissue engineering, 3D modeling, Nondestructive evaluation, Animal model studies, 3D printing, X-ray imaging, Phase contrast

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Proceedings Article | 18 October 2021 Open Access

Open Access

Presentation + Paper

High-speed grating interferometry

Shashidhara Marathe, Ralf Ziesche, Gunjan Das, Sven Schroeder, Emily Baird, Christoph Rau

Proceedings Volume 11840, 118400L (2021) https://doi.org/10.1117/12.2598481

KEYWORDS: X-rays, Visibility, Crystals, Tomography, X-ray imaging, Optical filters, Spatial coherence, Interferometers, Image filtering, Head

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Proceedings Article | 15 October 2021 Open Access

Open Access

Poster + Paper

Operando and high-throughput multiscale-tomography

Christoph Rau, Shashidhara Marathe, Andrew Bodey, Malte Storm, Darren Batey, Silvia Cipiccia, Peng Li, Ralf Ziesche

Proceedings Volume 11840, 118401E (2021) https://doi.org/10.1117/12.2598470

KEYWORDS: Diamond, Monochromators, Data acquisition, Crystals, Tomography, Crystallography, Phase contrast, X-rays, Spatial resolution, Optical filters

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We report about multiscale tomography with high throughput at the Diamond beamline I13L. The beamline has the purpose of multi-scale and operando imaging and consists of two independent branchlines operating in real and reciprocal space. The imaging branch -called Diamond-Manchester branchline- hosts micro-tomography, grating interferometry and a full-field microscope. For rapid recording a broad spectrum of the undulator radiation is used either with band-passing the light with a combination of a filter and a deflecting mirror or using a multilayer monochromator. For all the methods similar recording times can be achieved, with typical scanning times of some minutes and covering the resolution range from microns to the 100nm range. Most recently a robot arm has been installed to increase the throughput to 300 samples per day. The system is now implemented for user operation in remote operation mode for the micro-tomography setup and can be expanded to the two other experiments. The instrumental capabilities are applied on various topics such as the study of biodiversity of insects or the structural variations of electrode materials in batteries. Fast recording with dedicated sample environments (not using the sample changing robot) enables operando studies in many areas, the charging/discharging cycles on batteries, the degradation of teeth enamel under various conditions or loading brine sandstone mixtures with CO2, to name some examples. For imaging with highest spatial resolution we managed to improve significantly the recording speed of ptycho-tomography, which is now in the order of hours and will be reduced further. We demonstrated in the past 2-D recording with 10kHz and expand the instrumental capability with specific hardware dependent triggering and scanning schemes. We expand the research program for multi-scale imaging across both branchlines (imaging and coherence branchlines) with first studies such as batteries, brain research, concrete.

Proceedings Article | 1 August 2021 Presentation

Presentation

Fast multi-scale x-ray imaging

Christoph Rau, Darren Batey, Andrew Bodey, Silvia Cipiccia, Peng Li, Shashidhara Marathe, Malte Storm, Gunjan Das, Ralf Ziesche

Proceedings Volume 11839, 1183906 (2021) https://doi.org/10.1117/12.2596477

KEYWORDS: X-ray imaging, Imaging systems, Tomography, Diamond

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Proceedings Article | 16 October 2019 Open Access

Open Access

Presentation + Paper

Development of synchrotron pink beam x-ray grating interferometer at the Diamond Light source I13-2 beamline

Shashidhara Marathe, Malte Storm, Venkata S. C. Kuppilli, Richard Harrison, Gunjan Das, Sven L. M. Schroeder, Silvia Cipiccia, Florian Döring, Christian David, Christoph Rau

Proceedings Volume 11113, 1111319 (2019) https://doi.org/10.1117/12.2530698

KEYWORDS: X-rays, Crystals, Interferometers, X-ray imaging, Mirrors, Sensors, Signal attenuation, Image processing, Synchrotrons, Tomography

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Proceedings Article | 1 October 2019 Open Access

Open Access

Presentation + Paper

New imaging opportunities at the DIAMOND beamline I13L

C. Rau, D. Batey, S. Cipiccia, X. Shi, S. Marathe, M. Storm, A. Bodey, M. Zdora

Proceedings Volume 11112, 111120L (2019) https://doi.org/10.1117/12.2543799

KEYWORDS: Sensors, Diamond, Phase contrast, Spatial resolution, Control systems, Interferometry, Mirrors, Monochromators, Image resolution, Coherence (optics)

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Proceedings Article | 1 October 2019 Open Access

Open Access

Presentation + Paper

Fast Multi-scale imaging using the Beamline I13L at the Diamond Light Source

C. Rau, M. Storm, S. Marathe, A. Bodey, M. Zdora, S. Cipiccia, D. Batey, X. Shi, S. M. L. Schroeder, G. Das, M. Loveridge, R. Ziesche, B. Connolly

Proceedings Volume 11113, 111130P (2019) https://doi.org/10.1117/12.2543405

KEYWORDS: Crystals, Microscopes, X-rays, Monochromators, Mirrors, Diamond, Phase contrast, Tomography, Optical filters, Interferometry

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SPIE Journal Paper | 23 October 2018 Open Access

Open Access

Multichannel optrodes for photonic stimulation

Yingyue Xu, Nan Xia, Michelle Lim, Xiaodong Tan, Minh Ha Tran, Erin Boulger, Fei Peng, Hunter Young, Christoph Rau, Alexander Rack, Claus-Peter Richter

NPh, Vol. 5, Issue 04, 045002, (October 2018) https://doi.org/10.1117/12.10.1117/1.NPh.5.4.045002

KEYWORDS: Optical fibers, Electrodes, Vertical cavity surface emitting lasers, Light sources, Tissue optics, Infrared radiation, Photons, Waveguides, Light emitting diodes, Neurons

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Proceedings Article | 18 September 2018 Presentation + Paper

Presentation + Paper

Inspecting adaptive optics with at-wavelength wavefront metrology

J. Krempaský, F. Koch, P. Vagovič, L. Mikeš, A. Jaggi, C. Svetina, U. Flechsig, L. Patthey, S. Marathe, D. Batey, S. Cipiccia, C. Rau, F. Seiboth, M. Seaberg, C. David, U. Wagner

Proceedings Volume 10761, 107610D (2018) https://doi.org/10.1117/12.2320532

KEYWORDS: Mirrors, X-rays, Adaptive optics, X-ray optics, Wavefront distortions, Wavefront analysis, Lenses, Wavefront metrology, Light sources, Wavefront aberrations

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Proceedings Article | 11 October 2017 Open Access

Open Access

Paper

Comparison of data processing techniques for single-grating x-ray Talbot interferometer data

Shashidhara Marathe, Marie-Christine Zdora, Irene Zanette, Silvia Cipiccia, Christoph Rau

Proceedings Volume 10391, 103910S (2017) https://doi.org/10.1117/12.2274021

KEYWORDS: Picosecond phenomena, X-rays, Spatial resolution, Interferometers, Sensors, Data processing, X-ray imaging, Image processing, Fourier transforms

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Proceedings Article | 11 October 2017 Open Access

Open Access

Presentation + Paper

Micro- and nano-tomography at the DIAMOND beamline I13L imaging and coherence

C. Rau, A. Bodey, M. Storm, S. Cipiccia, S. Marathe, M.-C. Zdora, I. Zanette, U. Wagner, D. Batey, X. Shi

Proceedings Volume 10391, 103910T (2017) https://doi.org/10.1117/12.2274514

KEYWORDS: Sensors, Diamond, Coherence imaging, Phase contrast, Coherence (optics), Spatial resolution, Microscopes, Image resolution, Tomography, CMOS sensors

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Proceedings Article | 3 October 2017 Presentation

Presentation

The imaging and coherence beamline I13L at DIAMOND (Conference Presentation)

Christoph Rau, Ulrich Wagner, Malte Ogurreck, Xiaowen Shi, Darren Batey, Silvia Cipiccia, Shashidhara Marathe, Andrew Bodey, Marie-Christine Zdora, Irene Zanette, Mirna Saliba, Venkata S. Kuppili, Simone Sala, Stefanos Chalkidis, Pierre Thibault

Proceedings Volume 10389, 1038905 (2017) https://doi.org/10.1117/12.2274501

KEYWORDS: Coherence imaging, Coherence (optics), Diamond, X-rays, Spatial resolution, Microscopy, Sensors, Diffraction, Synchrotrons, Tomography

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Proceedings Article | 23 August 2017 Paper

Paper

Aberration correction for hard x-ray focusing at the nanoscale

Frank Seiboth, Andreas Schropp, Maria Scholz, Felix Wittwer, Christian Rödel, Martin Wünsche, Tobias Ullsperger, Stefan Nolte, Jussi Rahomäki, Karolis Parfeniukas, Stylianos Giakoumidis, Ulrich Vogt, Ulrich Wagner, Christoph Rau, Ulrike Boesenberg, Jan Garrevoet, Gerald Falkenberg, Eric Galtier, Hae Ja Lee, Bob Nagler, Christian Schroer

Proceedings Volume 10386, 103860A (2017) https://doi.org/10.1117/12.2274030

KEYWORDS: X-ray optics, X-rays, X-ray diffraction, Synchrotron radiation, Reflectivity, X-ray characterization, Glasses, Optical testing, Aberration correction, Femtosecond phenomena, Wavefront reconstruction, Wavefront aberrations, Wavefront analysis, Wavefront compensation

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Proceedings Article | 18 February 2011 Paper

Paper

Phase contrast imaging of cochlear soft tissue

Stephanie Shintani Smith, Margaret Hwang, Christoph Rau, Andrew Fishman, Wah-Keat Lee, Claus-Peter Richter

Proceedings Volume 7883, 788323 (2011) https://doi.org/10.1117/12.882949

KEYWORDS: Phase contrast, Tissues, Tomography, X-rays, X-ray imaging, Absorption, Imaging systems, Tissue optics, Hard x-rays, Radiography

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Proceedings Article | 7 September 2006 Paper

Paper

A hard x-ray KB-FZP microscope for tomography with sub-100-nm resolution

C. Rau, V. Crecea, C.-P. Richter, K. Peterson, P. Jemian, U. Neuhäusler, G. Schneider, X. Yu, P. Braun, T.-C. Chiang, I. Robinson

Proceedings Volume 6318, 63181G (2006) https://doi.org/10.1117/12.680975

KEYWORDS: Microscopes, Tomography, Hard x-rays, Phase contrast, Photonic crystals, Zone plates, Sensors, Mirrors, X-rays, Objectives

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Proceedings Article | 26 October 2004 Paper

Paper

The evolution of hard x-ray tomography from the micrometer to the nanometer length scale

Christoph Rau, K. Peterson, P. Jemian, T. Terry, Michael Harris, Stefan Vogt, C.-P. Richter, U. Neuhausler, G. Schneider, Ian Robinson

Proceedings Volume 5535, (2004) https://doi.org/10.1117/12.559887

KEYWORDS: Tomography, Microscopes, Hard x-rays, Zone plates, Phase contrast, Mirrors, X-rays, Objectives, Phase shifts, Spatial resolution

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Proceedings Article | 26 October 2004 Paper

Paper

Nanotomography using parabolic refractive x-ray lenses

Christian Schroer, Boris Benner, Til Florian Gunzler, Marion Kuhlmann, Jens Patommel, Bruno Lengeler, Andrea Somogyi, Timm Weitkamp, Christoph Rau, Anatoly Snigirev, Irina Snigireva

Proceedings Volume 5535, (2004) https://doi.org/10.1117/12.559643

KEYWORDS: X-rays, Lenses, Microscopes, Beryllium, Hard x-rays, Spatial resolution, Tomography, X-ray microscopy, Sensors, X-ray imaging

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Proceedings Article | 26 October 2004 Paper

Paper

Microstructural characterization in 3D: the key to understanding grain growth in polycrystalline materials?

Carl Krill, Kristian Dobrich, Markus Ziehmer, Christoph Rau

Proceedings Volume 5535, (2004) https://doi.org/10.1117/12.559827

KEYWORDS: Tin, Aluminum, Correlation function, 3D microstructuring, Tomography, Crystals, X-rays, Solids, Chemical species, Annealing

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Proceedings Article | 26 October 2004 Paper

Paper

Tomography with chemical speciation

Christoph Rau, Andrea Somogyi, Alexandre Simionovici

Proceedings Volume 5535, (2004) https://doi.org/10.1117/12.558825

KEYWORDS: Tomography, Absorption, X-rays, Chemical species, Sensors, Chemical analysis, Spectroscopy, Chemical elements, Molybdenum, Capillaries

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Proceedings Article | 21 November 2002 Paper

Paper

Beryllium parabolic refractive x-ray lenses

Christian Schroer, Marion Kuhlmann, Bruno Lengeler, Til Gunzler, O. Kurapova, Boris Benner, Christoph Rau, Alexandre Simionovici, Anatoly Snigirev, Irina Snigireva

Proceedings Volume 4783, (2002) https://doi.org/10.1117/12.451013

KEYWORDS: Lenses, Beryllium, X-rays, Aluminum, Image resolution, Microscopy, Hard x-rays, X-ray imaging, Photomicroscopy, X-ray optics

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Proceedings Article | 7 January 2002 Paper

Paper

Tomographic characterization of grain-size correlations in polycrystalline Al-Sn

Carl Krill, Kristian Deobrich, Daniel Michels, Andreas Michels, Christoph Rau, Timm Weitkamp, Anatoly Snigirev, Rainer Birringer

Proceedings Volume 4503, (2002) https://doi.org/10.1117/12.452836

KEYWORDS: Tin, Tomography, Aluminum, Chemical species, Correlation function, Absorption, Optical spheres, Computer simulations, Reconstruction algorithms, X-rays

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Proceedings Article | 7 January 2002 Paper

Paper

Magnified hard x-ray microtomography: toward tomography with submicron resolution

Christian Schroer, Boris Benner, Til Guenzler, Marion Kuhlmann, Bruno Lengeler, Christoph Rau, Timm Weitkamp, Anatoly Snigirev, Irina Snigireva

Proceedings Volume 4503, (2002) https://doi.org/10.1117/12.452858

KEYWORDS: Tomography, Microscopes, X-rays, Hard x-rays, Lenses, Photomicroscopy, Absorption, X-ray imaging, Sensors, Phase contrast

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Proceedings Article | 7 January 2002 Paper

Paper

Tomography with high resolution

Christoph Rau, Timm Weitkamp, Anatoly Snigirev, Christian Schroer, Boris Benner, Johannes Tuemmler, Til Guenzler, Marion Kuhlmann, Bruno Lengeler, Carl Krill, K. Doebrich, Daniel Michels, Andreas Michels

Proceedings Volume 4503, (2002) https://doi.org/10.1117/12.452849

KEYWORDS: Tomography, X-rays, Mirrors, Aluminum, Silicon, Hard x-rays, Palladium, X-ray imaging, Spatial resolution, Sensors

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Proceedings Article | 7 January 2002 Paper

Paper

XANES micro-imaging and tomography

Christoph Rau, Andrea Somogyi, A. Bytchkov, Alexandre Simionovici

Proceedings Volume 4503, (2002) https://doi.org/10.1117/12.452851

KEYWORDS: Tomography, Absorption, X-rays, Sensors, Chemical elements, Capillaries, Imaging systems, Molybdenum, Chemistry, Oxidation

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Proceedings Article | 7 January 2002 Paper

Paper

Nondestructive three-dimensional evaluation of biocompatible materials by microtomography using synchrotron radiation

Bert Muller, Philipp Thurner, Felix Beckmann, Timm Weitkamp, Christoph Rau, Ricardo Bernhardt, Erdal Karamuk, Ludwig Eckert, J. Brandt, Stefan Buchloh, Erich Wintermantel, Dieter Scharnweber, Hartmut Worch

Proceedings Volume 4503, (2002) https://doi.org/10.1117/12.452843

KEYWORDS: Bone, Tissues, Spatial resolution, Optical spheres, Polymers, Titanium, Modulation transfer functions, Human-machine interfaces, Synchrotron radiation, X-rays

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Proceedings Article | 7 January 2002 Paper

Paper

In-line phase contrast in synchrotron-radiation microradiography and tomography

Timm Weitkamp, Christoph Rau, Anatoly Snigirev, Boris Benner, Til Guenzler, Marion Kuhlmann, Christian Schroer

Proceedings Volume 4503, (2002) https://doi.org/10.1117/12.452832

KEYWORDS: Phase contrast, Tomography, Absorption, X-rays, Microscopes, Wave propagation, Sensors, Lenses, X-ray imaging, Wavefronts

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Proceedings Article | 13 December 2001 Paper

Paper

Refractive and diffractive x-ray optical elements

Irina Snigireva, Anatoly Snigirev, Serguei Kuznetsov, Christoph Rau, Timm Weitkamp, Leonid Shabelnikov, Michail Grigoriev, Vecheslav Yunkin, Martin Hoffmann, Edgar Voges

Proceedings Volume 4499, (2001) https://doi.org/10.1117/12.450223

KEYWORDS: Computer generated holography, X-rays, Silicon, Absorption, Lens design, Chlorine, Manufacturing, Etching, Synchrotron radiation, X-ray imaging

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Proceedings Article | 5 January 2001 Paper

Paper

Parabolic compound refractive lenses for hard x rays

Christian Schroer, Bruno Lengeler, Boris Benner, Marion Kuhlmann, Til Guenzler, Johannes Tuemmler, Christoph Rau, Timm Weitkamp, Anatoly Snigirev, Irina Snigireva

Proceedings Volume 4145, (2001) https://doi.org/10.1117/12.411647

KEYWORDS: Lenses, Aluminum, X-rays, Hard x-rays, Beryllium, Microscopy, Microscopes, Absorption, Synchrotrons, Tomography

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Proceedings Article | 5 January 2001 Paper

Paper

Silicon planar parabolic lenses

Vitaly Aristov, Michail Grigoriev, Serguei Kuznetsov, Leonid Shabelnikov, Vecheslav Yunkin, Christoph Rau, Anatoly Snigirev, Irina Snigireva, Timm Weitkamp, Martin Hoffmann, Edgar Voges

Proceedings Volume 4145, (2001) https://doi.org/10.1117/12.411648

KEYWORDS: Lenses, Silicon, Absorption, X-rays, Diamond, Microfabrication, Synchrotron radiation, Etching, Hard x-rays, X-ray optics

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Showing 5 of 31 publications

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