Prof. Cornelis H. Slump Profile

Prof. Cornelis H. Slump

Full Professor at Univ Twente

SPIE Involvement:

Author

Publications (57)

SPIE Journal Paper | 11 February 2023

Unsupervised convolutional autoencoders for 4D transperineal ultrasound classification

Frieda Van den Noort, Claudia Manzini, Merijn Hofsteenge, Beril Sirmacek, Carl Van der Vaart, Cornelis H. Slump

JMI, Vol. 10, Issue 01, 014004, (February 2023) https://doi.org/10.1117/12.10.1117/1.JMI.10.1.014004

KEYWORDS: Education and training, Ultrasonography, Muscles, Principal component analysis, Statistical analysis, Motion analysis, Data modeling, Diseases and disorders, Design and modelling, Visualization

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Proceedings Article | 4 April 2022 Poster + Paper

Evaluation of a cardiac flow phantom for absolute myocardial perfusion SPECT measurements

M. Kamphuis, Marcel J. W. Greuter, R. H. J. Slart, Cornelis Slump

Proceedings Volume 12036, 1203626 (2022) https://doi.org/10.1117/12.2623667

KEYWORDS: Single photon emission computed tomography, Data modeling, Differential equations, Positron emission tomography, Standards development, Software validation

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SPIE Journal Paper | 13 January 2021 Open Access

In vitro performance of echoPIV for assessment of laminar flow profiles in a carotid artery stent

Astrid Hoving, Jason Voorneveld, Julia Mikhal, Johan Bosch, Erik Groot Jebbink, Cornelis Slump

JMI, Vol. 8, Issue 01, 017001, (January 2021) https://doi.org/10.1117/12.10.1117/1.JMI.8.1.017001

KEYWORDS: Ultrasonography, In vitro testing, Arteries, Blood circulation, Statistical analysis, In vivo imaging, Blood, Velocity measurements, Particle image velocimetry, Metals

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Proceedings Article | 25 February 2020 Paper

Intraoperative specimen assessment in prostate cancer surgery using Cerenkov luminescence imaging

J. olde Heuvel, B. de Wit-van der Veen, H. van der Poel, M. P. Stokkel, C. Slump

Proceedings Volume 11224, 1122407 (2020) https://doi.org/10.1117/12.2542650

KEYWORDS: Prostate, Tumors, Gallium, Tissues, Surgery, Optical filters, Prostate cancer, Cerenkov radiation imaging

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Proceedings Article | 8 March 2019 Paper

Fully resolved simulation and ultrasound flow studies in stented carotid aneurysm model

J. Mikhal, A. Hoving, G. Ong, C. Slump

Proceedings Volume 10951, 1095115 (2019) https://doi.org/10.1117/12.2513002

KEYWORDS: Aneurysms, 3D modeling, Ultrasonography, Process modeling, Arteries, Numerical simulations, Blood circulation, Computer simulations, In vitro testing, Visualization

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Introduction. Treatment choice for extracranial carotid artery widening, also called aneurysm, is difficult. Blood flow simulation and experimental visualization can be supportive in clinical decision making and patient-specific treatment prediction. This study aims to simulate and validate the effect of flow-diverting stent placement on blood flow characteristics using numerical and in vitro simulation techniques in simplified carotid artery and aneurysm models. Methods. We have developed a workflow from geometry design to flow simulations and in vitro measurements in a carotid aneurysm model. To show feasibility of the numerical simulation part of the workflow that uses an immersed boundary method, we study a model geometry of an extracranial carotid artery aneurysm and put a flow-diverting stent in the aneurysm. We use ultrasound particle image velocimetry (PIV) to visualize experimentally the flow inside the aneurysm model. Results. Feasibility of ultrasound visualization of the flow, virtual flow-diverting stent placement and numerical flow simulation are presented. Flow is resolved to scales much smaller than the cross section of individual wires of the flow-diverting stent. Numerical analysis in stented model introduced 25% reduction of the blood flow inside the aneurysm sac. Quantitative comparison of experimental and numerical results showed agreement in 1D velocity profiles. Discussion/conclusion. We find good numerical convergence of the simulations at appropriate spatial resolutions using the immersed boundary method. This allows us to quantify the changes in the flow in model geometries after deploying a flow-diverting stent. We visualized the physiological blood flow in a 1-to-1 aneurysm model, using PIV, showing a good correspondence to the numerical simulations. The novel workflow enables numerical as well as experimental flow simulations in patient-specific cases before and after flow-diverting stent placement. This may contribute to endovascular treatment prediction.

SPIE Journal Paper | 21 May 2018 Open Access

Detection of small traumatic hemorrhages using a computer-generated average human brain CT

Liza Afzali-Hashemi, Marieke Hazewinkel, Marleen Tjepkema-Cloostermans, Michel J. A. van Putten, Cornelis Slump

JMI, Vol. 5, Issue 02, 024004, (May 2018) https://doi.org/10.1117/12.10.1117/1.JMI.5.2.024004

KEYWORDS: Computed tomography, Traumatic brain injury, Image registration, Brain, Control systems, Neuroimaging, Feature extraction, Skull, Visualization, Image restoration

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Proceedings Article | 7 March 2018 Paper

Development of a validation instrument in myocardial perfusion imaging: results of first flow experiments

Marije Kamphuis, Gert Jan Pelgrim, Marcel Greuter, Riemer H. J. A. Slart, Cornelis Slump

Proceedings Volume 10577, 1057714 (2018) https://doi.org/10.1117/12.2286337

KEYWORDS: Computed tomography, Sensors, Computer aided diagnosis and therapy, Device simulation, Computer aided design, Data acquisition, Blood circulation, Heart

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Proceedings Article | 6 March 2018 Paper

In vitro high-frame-rate contrast-enhanced ultrasound particle image velocimetry in a carotid artery stent

Astrid Hoving, Jason Voorneveld, Evelien de Vries, Erik Groot Jebbink, Michel Versluis, Johan Bosch, Nico de Jong, Julia Mikhal, Gert de Borst, Cornelis Slump

Proceedings Volume 10580, 105800A (2018) https://doi.org/10.1117/12.2293669

KEYWORDS: Ultrasonography, Arteries, In vitro testing, Numerical simulations, Silicon, Transducers, Particle image velocimetry, Blood circulation, Velocity measurements, Computer simulations

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Proceedings Article | 3 March 2017 Paper

Validation of an image registration and segmentation method to measure stent graft motion on ECG-gated CT using a physical dynamic stent graft model

Maaike Koenrades, Ella Struijs, Almar Klein, Henny Kuipers, Robert Geelkerken, Cornelis Slump

Proceedings Volume 10134, 1013418 (2017) https://doi.org/10.1117/12.2254262

KEYWORDS: 4D CT imaging, Vascular imaging, Motion measurement, Device simulation, Image processing algorithms and systems, Data modeling, Image registration, Image segmentation, Computed tomography, Detection and tracking algorithms, Motion models, Scanners, Motion detection, Cameras, Temporal resolution

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Proceedings Article | 24 March 2016 Paper

Automatic determination of white matter hyperintensity properties in relation to the development of Alzheimer's disease

Sandra van der Velden, Christoph Moenninghoff, Isabel Wanke, Martha Jokisch, Christian Weimar, Rita Lopes Simoes, Anne-Marie van Cappellen van Walsum, Cornelis Slump

Proceedings Volume 9785, 97852D (2016) https://doi.org/10.1117/12.2216369

KEYWORDS: Alzheimer's disease, Algorithm development, Control systems, Medicine, Brain, Magnetic resonance imaging, Dementia, Image segmentation, Image registration, Head

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Proceedings Article | 24 March 2016 Paper

Segmentation and determination of joint space width in foot radiographs

O. Schenk, D. de Muinck Keizer, H. Bernelot Moens, C. Slump

Proceedings Volume 9785, 97853G (2016) https://doi.org/10.1117/12.2216873

KEYWORDS: Radiography, Bone, Image segmentation, Algorithm development, Visualization, Image analysis, Image processing algorithms and systems, Databases, Rheumatology, CAD systems, Data modeling

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SPIE Journal Paper | 24 March 2015 Open Access

Automated brain computed tomographic densitometry of early ischemic changes in acute stroke

Berend Stoel, Henk Marquering, Marius Staring, Ludo Beenen, Cornelis Slump, Yvo Roos, Charles Majoie

JMI, Vol. 2, Issue 01, 014004, (March 2015) https://doi.org/10.1117/12.10.1117/1.JMI.2.1.014004

KEYWORDS: Brain, Neuroimaging, Densitometry, Computed tomography, Image segmentation, Tomography, Image registration, Magnetic resonance imaging, Tissues, Ischemic stroke

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Proceedings Article | 20 March 2015 Paper

A novel framework for the temporal analysis of bone mineral density in metastatic lesions using CT images of the femur

Tom Knoop, Loes Derikx, Nico Verdonschot, Cornelis Slump

Proceedings Volume 9414, 94143A (2015) https://doi.org/10.1117/12.2081916

KEYWORDS: Bone, Calibration, Polymethylmethacrylate, Calcium, Computed tomography, Minerals, Radiotherapy, Analytical research, Magnesium, In vitro testing

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Proceedings Article | 17 March 2015 Paper

Toward automatic segmentation and quantification of tumor and stroma in whole-slide images of H and E stained rectal carcinomas

Oscar Geessink, Alexi Baidoshvili, Gerard Freling, Joost Klaase, Cornelis Slump, Ferdinand van der Heijden

Proceedings Volume 9420, 94200F (2015) https://doi.org/10.1117/12.2081665

KEYWORDS: Tumors, Image segmentation, Tissues, Colorectal cancer, Cancer, Visualization, Error control coding, Algorithm development, Image classification, Microscopy

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Proceedings Article | 20 March 2014 Paper

The effects of probe placement on measured flow velocity in transcranial Doppler ultrasound imaging in-vitro and in-vivo experiments

Daan L. de Jong, Aisha S. Meel-van den Abeelen, Joep Lagro, Jurgen Claassen, Cornelis Slump

Proceedings Volume 9040, 904020 (2014) https://doi.org/10.1117/12.2042329

KEYWORDS: In vitro testing, Velocity measurements, Doppler effect, In vivo imaging, Blood, Bone, Skull, Ultrasonography, Brain, Signal detection

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Proceedings Article | 18 March 2014 Paper

Early detection of Alzheimer's disease using histograms in a dissimilarity-based classification framework

Anne Luchtenberg, Rita Simões, Anne-Marie van Cappellen van Walsum, Cornelis Slump

Proceedings Volume 9035, 903502 (2014) https://doi.org/10.1117/12.2042670

KEYWORDS: Distance measurement, Alzheimer's disease, Brain, Dementia, Control systems, Magnetic resonance imaging, Neuroimaging, Tissues, Image segmentation, Electroluminescent displays

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Proceedings Article | 12 March 2014 Paper

Innovation in aortoiliac stenting: an in vitro comparison

E. Groot Jebbink, P. C. J. Goverde, J. van Oostayen, M. M. P. Reijnen, C. Slump

Proceedings Volume 9036, 90361X (2014) https://doi.org/10.1117/12.2042865

KEYWORDS: Metals, Surgery, In vitro testing, Hemodynamics, Blood, Blood circulation, Arteries, Neodymium, Visualization, Coating

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Proceedings Article | 14 April 2012 Paper

A comparison of two methods to segment stent grafts in CT data

Almar Klein, Michel Klaassen, Luuk Oostveen, J. Adam van der Vliet, Yvonne Hoogeveen, Leo Schultze Kool, W. KlaasJan Renema, Cornelis Slump

Proceedings Volume 8317, 83170H (2012) https://doi.org/10.1117/12.911296

KEYWORDS: 3D modeling, Microchannel plates, Image segmentation, Data modeling, Computed tomography, Failure analysis, Motion models, Detection and tracking algorithms, 3D image processing, Corner detection

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Proceedings Article | 23 February 2012 Paper

Automatic histogram-based segmentation of white matter hyperintensities using 3D FLAIR images

Rita Simões, Cornelis Slump, Christoph Moenninghoff, Isabel Wanke, Martha Dlugaj, Christian Weimar

Proceedings Volume 8315, 83153K (2012) https://doi.org/10.1117/12.911327

KEYWORDS: Image segmentation, Expectation maximization algorithms, Magnetic resonance imaging, Brain, 3D image processing, Data modeling, Binary data, Neuroimaging, Fuzzy logic, Biomedical optics

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Proceedings Article | 23 February 2012 Paper

MRI based knee cartilage assessment

Dirk-Jan Kroon, Przemyslaw Kowalski, Wojciech Tekieli, Els Reeuwijk, Daniel Saris, Cornelis Slump

Proceedings Volume 8315, 83151V (2012) https://doi.org/10.1117/12.906918

KEYWORDS: Cartilage, Bone, Magnetic resonance imaging, Image segmentation, Brain-machine interfaces, Data modeling, Interfaces, Medical imaging, Medicine, Visualization

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Proceedings Article | 16 March 2011 Paper

Comparison of dynamic susceptibility contrast-MRI perfusion quantification methods in the presence of delay and dispersion

Bianca Maan, Rita Lopes Simões, Frederick J. Meijer, W. Klaas Jan Renema, Cornelis Slump

Proceedings Volume 7965, 79652C (2011) https://doi.org/10.1117/12.878177

KEYWORDS: Tissues, Signal to noise ratio, Brain, Deconvolution, Magnetic resonance imaging, Blood circulation, Neuroimaging, Blood, Error analysis, Ischemic stroke

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Proceedings Article | 12 March 2011 Paper

Multimodal image registration by edge attraction and regularization using a B-spline grid

Almar Klein, Dirk-Jan Kroon, Yvonne Hoogeveen, Leo Schultze Kool, W. Klaas Jan Renema, Cornelis Slump

Proceedings Volume 7962, 796220 (2011) https://doi.org/10.1117/12.878267

KEYWORDS: Image registration, Image processing, Diffusion, Medical imaging, Image restoration, Image analysis, Analog electronics, Magnetic resonance imaging, Visualization, Medical diagnostics

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Proceedings Article | 9 March 2011 Paper

Development of automated quantification of visceral and subcutaneous adipose tissue volumes from abdominal CT scans

Sanne Mensink, Jarich Spliethoff, Ruben Belder, Joost Klaase, Roland Bezooijen, Cornelis Slump

Proceedings Volume 7963, 79632Q (2011) https://doi.org/10.1117/12.878017

KEYWORDS: Tissues, Image segmentation, Computed tomography, Surgery, Algorithm development, Computer simulations, Image processing algorithms and systems, Image processing, Colorectal cancer, Signal attenuation

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Proceedings Article | 23 February 2011 Paper

On the role of passive elements in photoacoustic reconstruction

Cornelis Slump, Rene G. Willemink, Srirang Manohar, Bernhard Hoenders

Proceedings Volume 7899, 78993G (2011) https://doi.org/10.1117/12.875327

KEYWORDS: Passive elements, Acoustics, Numerical simulations, Ultrasonography, Pulsed laser operation, Absorption, Photoacoustic spectroscopy, Reconstruction algorithms, Tissue optics, 3D modeling

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Proceedings Article | 9 March 2010 Paper

Automated myocardial perfusion from coronary x-ray angiography

Corstiaan Storm, Cornelis Slump

Proceedings Volume 7624, 76242S (2010) https://doi.org/10.1117/12.840018

KEYWORDS: Angiography, Electrocardiography, Arteries, X-rays, Heart, Blood, Image segmentation, Blood circulation, Signal detection, Nuclear medicine

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Proceedings Article | 14 March 2009 Paper

Diagnostic quality of time-averaged ECG-gated CT data

Almar Klein, Luuk Oostveen, Marcel J. Greuter, Yvonne Hoogeveen, Leo Schultze Kool, Cornelis Slump, W. Klaas Jan Renema

Proceedings Volume 7258, 725836 (2009) https://doi.org/10.1117/12.807271

KEYWORDS: Modulation transfer functions, Computed tomography, Electrocardiography, Scanners, Diagnostics, Phase shift keying, Visualization, Data acquisition, Image quality, Spatial frequencies

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Proceedings Article | 13 March 2009 Paper

Simultaneous imaging of ultrasound attenuation, speed of sound, and optical absorption in a photoacoustic setup

Rene G. H. Willemink, Srirang Manohar, Jithin Jose, Kees Slump, Ferdi van der Heijden, Ton G. van Leeuwen

Proceedings Volume 7265, 72650J (2009) https://doi.org/10.1117/12.810905

KEYWORDS: Absorption, Acoustics, Photoacoustic spectroscopy, Reconstruction algorithms, Signal attenuation, Ultrasonography, Sensors, Passive elements, Refraction, Photoacoustic imaging

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Proceedings Article | 3 April 2008 Paper

A segmentation method for stentgrafts in the abdominal aorta from ECG-gated CTA data

Almar Klein, W. KlaasJan Renema, Luuk Oostveen, Leo Schultze Kool, Cornelis Slump

Proceedings Volume 6916, 69160R (2008) https://doi.org/10.1117/12.770064

KEYWORDS: Image segmentation, Detection and tracking algorithms, Computed tomography, Image processing algorithms and systems, Metals, Hemodynamics, Visualization, Databases, Safety, Medical imaging

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Proceedings Article | 18 March 2008 Paper

Estimation of x-ray parameters in digital coronary angiography for compensation of myocardial perfusion measurements

Corstiaan Storm, Cornelis Slump

Proceedings Volume 6913, 69133L (2008) https://doi.org/10.1117/12.770761

KEYWORDS: Angiography, X-rays, Arteries, Electrocardiography, Camera shutters, Image analysis, Heart, Imaging systems, X-ray imaging, Automatic exposure

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Proceedings Article | 13 March 2008 Paper

Photoacoustic 3D visualization of tumor angiogenesis

G. ten Brinke, R. Kolkman, C. Slump, W. Steenbergen

Proceedings Volume 6920, 692012 (2008) https://doi.org/10.1117/12.769449

KEYWORDS: Tumors, Photoacoustic spectroscopy, Visualization, 3D image processing, Sensors, Ultrasonography, 3D visualizations, Photoacoustic imaging, Transducers, Blood vessels

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Proceedings Article | 10 March 2008 Paper

Imaging of acoustic attenuation and speed of sound maps using photoacoustic measurements

Rene Willemink, Srirang Manohar, Yashasvi Purwar, Cornelis Slump, Ferdi van der Heijden, Ton van Leeuwen

Proceedings Volume 6920, 692013 (2008) https://doi.org/10.1117/12.770061

KEYWORDS: Acoustics, Signal attenuation, Sensors, Passive elements, Absorption, Ultrasonography, Chemical elements, Photoacoustic spectroscopy, Calibration, Time metrology

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Proceedings Article | 17 July 2007 Paper

Acoustic property measurements in a photoacoustic imager

René Willemink, Srirang Manohar, Cornelis Slump, Ferdi van der Heijden, Ton van Leeuwen

Proceedings Volume 6631, 663109 (2007) https://doi.org/10.1117/12.728042

KEYWORDS: Acoustics, Sensors, Passive elements, Ultrasonography, Photoacoustic spectroscopy, Absorption, Calibration, Imaging systems, Tissue optics, Signal attenuation

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Proceedings Article | 30 March 2007 Paper

CAD of myocardial perfusion

Corstiaan Storm, Cornelis Slump

Proceedings Volume 6514, 65142D (2007) https://doi.org/10.1117/12.709330

KEYWORDS: Angiography, Arteries, Electrocardiography, Heart, Resistance, Signal detection, Algorithm development, Standards development, Blood circulation, Computer aided design

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Proceedings Article | 20 March 2006 Paper

Image based hemodynamic modeling of cerebral aneurysms and the determination of the risk of rupture

D. J. Kroon, C. Slump, M. Sluzewski, W. J. J. van Rooij

Proceedings Volume 6143, 61432B (2006) https://doi.org/10.1117/12.648062

KEYWORDS: Cerebral aneurysms, Arteries, 3D modeling, Hemodynamics, Angiography, Computer simulations, Blood vessels, Modeling, Diagnostics, Blood circulation

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Proceedings Article | 15 March 2006 Paper

Detection of joint space narrowing in hand radiographs

Joost Kauffman, Cornelis Slump, Hein Bernelot Moens

Proceedings Volume 6144, 614446 (2006) https://doi.org/10.1117/12.653584

KEYWORDS: Radiography, Distance measurement, Microchannel plates, Mahalanobis distance, Computer programming, Bone, Matrices, Edge detection, Rheumatology, Time metrology

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Proceedings Article | 13 March 2006 Paper

Digital densitometric determination of clinical relative coronary flow distributions

Gerhard ten Brinke, Cornelis Slump, Corstiaan Storm

Proceedings Volume 6143, 61432I (2006) https://doi.org/10.1117/12.648008

KEYWORDS: Arteries, Blood, X-rays, Velocity measurements, Detection and tracking algorithms, X-ray imaging, Angiography, Electrocardiography, Linear filtering, Image filtering

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Proceedings Article | 29 April 2005 Paper

Segmentation of hand radiographs by using multi-level connected active appearance models

Joost Kauffman, Cornelis Slump, Hein Bernelot Moens

Proceedings Volume 5747, (2005) https://doi.org/10.1117/12.595640

KEYWORDS: Image segmentation, Bone, Radiography, 3D modeling, Image processing algorithms and systems, Image resolution, Algorithm development, Medical imaging, Data modeling, Image processing

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Proceedings Article | 20 April 2005 Paper

On the ultimate x-ray detector for angiography

Cornelis Slump, Joost Kauffman

Proceedings Volume 5745, (2005) https://doi.org/10.1117/12.595170

KEYWORDS: Arteries, Angiography, X-ray detectors, Heart, Wave propagation, Sensors, X-rays, Motion models, Blood vessels, Blood circulation

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Proceedings Article | 30 May 2003 Paper

Volume estimation of cerebral aneurysms from biplane DSA: a comparison with measurements on 3D rotational angiography data

Javier Olivan Bescos, Marian Slob, Menno Sluzewski, Willem van Rooij, Cornelis Slump

Proceedings Volume 5029, (2003) https://doi.org/10.1117/12.480215

KEYWORDS: Angiography, 3D modeling, Image segmentation, Cerebral aneurysms, X-rays, 3D image processing, Blood vessels, X-ray imaging, Optical spheres, 3D metrology

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Proceedings Article | 18 April 2003 Paper

Natural learning of neural networks by reconfiguration

Lambert Spaanenburg, R. Alberts, Cornelis Slump, B. vanderZwaag

Proceedings Volume 5119, (2003) https://doi.org/10.1117/12.499549

KEYWORDS: Neural networks, Field programmable gate arrays, Neurons, Image processing, Logic, Computer programming, Computing systems, Very large scale integration, Matrices, Computer networks

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Proceedings Article | 17 May 2002 Paper

Interactive 4D cardiac MRI imaging based on iso-surface volume rendering

Javier Olivan Bescos, Jaap Smit, Cornelis Slump

Proceedings Volume 4681, (2002) https://doi.org/10.1117/12.466935

KEYWORDS: Visualization, Cardiovascular magnetic resonance imaging, Heart, Volume rendering, Data modeling, Magnetic resonance imaging, Data acquisition, Tissues, 3D modeling, Cardiovascular system

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Proceedings Article | 21 May 2001 Paper

Applying focal spot unsharpness to resolve ambiguity in 3D reconstruction from biplane coronary angiograms

Cornelis Slump, Marc Schrijver, Corstiaan Storm

Proceedings Volume 4321, (2001) https://doi.org/10.1117/12.428170

KEYWORDS: X-rays, Angiography, X-ray imaging, Blood vessels, Arteries, X-ray detectors, Sensors, Image acquisition, 3D modeling, Modulation transfer functions

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Proceedings Article | 21 May 2001 Paper

Myocardial fractional flow reserve: a biplane angiocardiographic alternative to the pressure gradient method

Marc Schrijver, Cornelis Slump, Corstiaan Storm

Proceedings Volume 4321, (2001) https://doi.org/10.1117/12.428172

KEYWORDS: Blood circulation, Arteries, Angiography, Image segmentation, Heart, Blood, Image acquisition, Estimation theory, Blood pressure, Densitometry

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Proceedings Article | 20 April 2000 Paper

Assessment of the pulse flow propagation based upon digital coronary angiograms

Cornelis Slump, Marc Schrijver, Henny Kuipers, Corstiaan Storm

Proceedings Volume 3978, (2000) https://doi.org/10.1117/12.383424

KEYWORDS: Arteries, Angiography, Heart, Blood, Motion models, Blood circulation, Image segmentation, Blood vessels, Image processing, Wave propagation

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Proceedings Article | 20 May 1999 Paper

Densitometric determination of the flow distribution in the bifurcation of the left coronary artery

Marc Schrijver, S. de Bondt, Cornelis Slump, Corstiaan Storm

Proceedings Volume 3660, (1999) https://doi.org/10.1117/12.349610

KEYWORDS: Arteries, Blood circulation, Tin, Blood, Angiography, Heart, Time metrology, X-rays, Toxic industrial chemicals, Autoregressive models

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Proceedings Article | 24 July 1998 Paper

Real-time diagnostic imaging with a novel x-ray detector with multiple screen-CCD sensors

Cornelis Slump, Pieter van Dijk, Geert-Jan Laanstra, Henny Kuipers, Mark Boer, Alex Nijmeijer, Rudolf Kemner, Henk Meulenbrugge, Ruud Snoeren

Proceedings Volume 3336, (1998) https://doi.org/10.1117/12.317042

KEYWORDS: Distortion, Sensors, Image quality, Image processing, Modulation transfer functions, Edge detection, CCD image sensors, X-ray detectors, Image resolution, Charge-coupled devices

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Proceedings Article | 3 July 1998 Paper

Tumor classification by means of eigenimage analysis of MRI perfusion scans

Marco Winkelman, Cornelis Slump, Jouke Smink, Jacques den Boer

Proceedings Volume 3337, (1998) https://doi.org/10.1117/12.312574

KEYWORDS: Tissues, Tumors, Brain, Magnetic resonance imaging, Image segmentation, Image filtering, Image enhancement, Algorithm development, Capillaries, Plasma

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Proceedings Article | 26 June 1998 Paper

Improving display quality by means of real-time image processing for multibeam CRTs

Cornelis Slump, H. Lalkens, Patrick Barels, Lex Lubbers, Rudolf Kemner

Proceedings Volume 3335, (1998) https://doi.org/10.1117/12.312530

KEYWORDS: Signal processing, Digital signal processing, CRTs, Filtering (signal processing), Optical filters, Video, Electronic filtering, Modulation transfer functions, Electron beams, Digital filtering

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Proceedings Article | 9 May 1997 Paper

Coronary artery diameter variations due to pulse-flow propagation

Cornelis Slump, Marco Winkelman, Remke Rutgers, Corstiaan Storm, Ad van Benthem

Proceedings Volume 3033, (1997) https://doi.org/10.1117/12.274044

KEYWORDS: Arteries, Image segmentation, Edge detection, Angiography, Image processing algorithms and systems, Image enhancement, Detection and tracking algorithms, Image processing, Algorithm development, Image filtering

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Proceedings Article | 7 May 1997 Paper

Lossy cardiac x-ray image compression based on acquisition noise

Frederik de Bruijn, Cornelis Slump

Proceedings Volume 3031, (1997) https://doi.org/10.1117/12.273908

KEYWORDS: Image compression, Interference (communication), Signal to noise ratio, Photons, X-ray imaging, Diagnostics, Imaging systems, Modulation transfer functions, X-rays, Video

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Proceedings Article | 7 May 1997 Paper

Assessment of image compression quality by means of quantitative coronary angiography

Cornelis Slump, Paul Hagendoorn, Remke Rutgers, Frederik de Bruijn, Corstiaan Storm, Ad van Benthem

Proceedings Volume 3031, (1997) https://doi.org/10.1117/12.273953

KEYWORDS: Image compression, Angiography, Image quality, Image segmentation, Diagnostics, Arteries, Distortion, Edge detection, Quantization, Polonium

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Proceedings Article | 2 May 1997 Paper

Image quality characteristics of a novel x-ray detector with multiple screen: CCD sensors for real-time diagnostic imaging

Cornelis Slump, Geert-Jan Laanstra, Henny Kuipers, Mark Boer, Alex Nijmeijer, Mark Bentum, Rudolf Kemner, Henk Meulenbrugge, Ruud Snoeren

Proceedings Volume 3032, (1997) https://doi.org/10.1117/12.274026

KEYWORDS: Distortion, Image quality, Sensors, Image processing, CCD image sensors, Charge-coupled devices, Modulation transfer functions, X-ray detectors, Image sensors, X-rays

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Proceedings Article | 15 April 1996 Paper

Improving display quality by a digital convergence correction system for multibeam CRTs

J. K. Patrick Barels, Albert Lubbers, Cornelis Slump, Rudolf Kemner, Aartjan Hoeven

Proceedings Volume 2707, (1996) https://doi.org/10.1117/12.238487

KEYWORDS: CRTs, Electron beams, Video, Modulation transfer functions, Visualization, Surgery, Medical imaging, Prototyping, Calibration, Computing systems

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Proceedings Article | 11 April 1996 Paper

Novel x-ray detector with multiple-screen-CCD sensors for real-time diagnostic imaging

Cornelis Slump, Geert-Jan Laanstra, Henny Kuipers, Mark Boer, Alex Nijmeijer, Mark Bentum, Rudolf Kemner, Henk Meulenbrugge, Ruud Snoeren

Proceedings Volume 2708, (1996) https://doi.org/10.1117/12.237807

KEYWORDS: Photons, CCD image sensors, Sensors, X-rays, Image quality, X-ray detectors, Fluoroscopy, Image sensors, Diagnostics, CCD cameras

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Proceedings Article | 16 September 1994 Paper

Efficient algorithm for two-dimensional finite impulse response (FIR) filtering and system identification

George-Othon Glentis, Cornelis Slump, Otto Herrmann

Proceedings Volume 2308, (1994) https://doi.org/10.1117/12.185963

KEYWORDS: Optical filters, Digital filtering, Algorithm development, Finite impulse response filters, System identification, Linear filtering, Curium, Image filtering, Line width roughness, Fermium

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Proceedings Article | 29 July 1993 Paper

Digital densitometric determination of relative coronary flow distributions

Albert Lubbers, Cornelis Slump, Corstiaan Storm

Proceedings Volume 1905, (1993) https://doi.org/10.1117/12.148639

KEYWORDS: Arteries, X-rays, Glasses, Heart, Blood circulation, Visualization, Video, Cardiology, In vitro testing, Image acquisition

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Proceedings Article | 1 June 1992 Paper

Restoration of noise aliasing and moire distortion in CCD-based diagnostic x-ray imaging

Cornelis Slump

Proceedings Volume 1652, (1992) https://doi.org/10.1117/12.59455

KEYWORDS: Moire patterns, Distortion, Image processing, Medical imaging, Photons, CCD image sensors, X-rays, Modulation transfer functions, X-ray imaging, Charge-coupled devices

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Sampling analog signals cause aliasing interference if the signal has frequency components higher than the folding frequency, i.e., half the sampling frequency. This distortion originates in the folding of these higher frequency components into the lower signal frequency spectrum with interference as a result. Usually aliasing artifacts are avoided by analog low-pass filtering of the signal prior to digitization. However, in the area of digitizing video signals from a CCD-based sensor such anti-alias filter is not feasible. The problem grows in importance due to increasing resolution requirements in many imaging applications pushing for CCD technology. This contribution reports the ongoing research to minimize the effects of two alias-based distortions, i.e., noise and moire patterns. In fluoroscopy, the amount of x-ray photons contributing to the image is restricted because of dose regulations. Quantum noise is clearly present in the images. The impinging white x-ray photons are spectrally shaped by the MTF of the imaging system. The resulting spectrum extends beyond the spatial Nyquist frequency of the CCD sensor. Aliased noise structures obscure diagnostic detail and, especially in real-time sequences, are annoying to look at. Another alias-based distortion is due to the anti-scatter grid, which is applied in order to reduce the number of scattered x-ray photons contributing to the image. Scattered photons give rise to a low-frequency blur of the images. An anti-scatter grid consists of a large number of parallel lead stripes separated by x- ray opaque material which are focussed at the x ray point source. The grid period is in the same order of magnitude as the CCD pixel size which causes moire pattern distortion in the images. In this contribution we discuss the restoration of both distortions. Aliased noise is minimized following a Wiener-type filtering approach. The moire pattern is attacked by inverse filtering. The analysis and simulations are presented, applications on medical images are shown.

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