High-resolution ultrasonic imaging has been increasingly used in dermatology as a complementary technique for cutaneous lesions assessment. The clinical application of ultra-high frequency ultrasound can reduce the number of invasive procedures, such as biopsies, and assist in surgical planning. The success of ultrasonic methods depends on the ability of modern imaging systems to deliver reliable and interpretable information. We present a new handheld high-resolution ultrasonic imager designed for dermatological use. The device operates at 50-100 MHz and provides B-scan images with up to 4 mm penetration depth and 40μm axial resolution. Adaptive signal processing algorithms allow highlighting anatomical and pathological features of the skin tissue. The primary skin layers, as well as the skin appendages, are clearly detectable on the obtained acoustical images. High-resolution characterization of skin morphology allows assessing the overall condition of the skin and can be used for diagnostic purposes. The new device will be useful for the number of dermatological applications: surgery planning and image-guided intervention, assessment of wound healing and skin grafts, vascular anomalies, inflammatory diseases, and numerous cosmetic complications.
We have developed a fingerprint software package that can be used in a wide range of applications from law enforcement to public and private security systems, and to personal devices such as laptops, vehicles, and door- locks. The software and processing units are a unique implementation of new and sophisticated algorithms that compete with the current best systems in the world. Development of the software package has been in line with the third generation of our ultrasonic fingerprinting machine1. Solid and robust performance is achieved in the presence of misplaced and low quality fingerprints.
Di Chen, Eugene Malyarenko, Fedar Seviaryn, Ye Yuan, Mark Sherman, Sudeshna Bandyopadhyay, Gretchen Gierach, Christopher Greenway, Elena Maeva, Emil Strumban, Neb Duric, Roman Maev
Objectives: The purpose of this study was to characterize human breast cancer tissues by the measurement of microacoustic properties.
Methods: We investigated eight breast cancer patients using acoustic microscopy. For each patient, seven blocks of tumor tissue were collected from seven different positions around a tumor mass. Frozen sections (10 micrometer, μm) of human breast cancer tissues without staining and fixation were examined in a scanning acoustic microscope with focused transducers at 80 and 200 MHz. Hematoxylin and Eosin (H and E) stained sections from the same frozen breast cancer tissues were imaged by optical microscopy for comparison.
Results: The results of acoustic imaging showed that acoustic attenuation and sound speed in cancer cell-rich tissue regions were significantly decreased compared with the surrounding tissue regions, where most components are normal cells/tissues, such as fibroblasts, connective tissue and lymphocytes. Our observation also showed that the ultrasonic properties were influenced by arrangements of cells and tissue patterns.
Conclusions: Our data demonstrate that attenuation and sound speed imaging can provide biomechanical information of the tumor and normal tissues. The results also demonstrate the potential of acoustic microscopy as an auxiliary method for operative detection and localization of cancer affected regions.
The objective of this research is to develop a new robust fingerprint identification technology based upon forming
surface-subsurface (under skin) ultrasonic 3D images of the finger pads. The presented work aims to create specialized
ultrasonic scanning methods for biometric purposes. Preliminary research has demonstrated the applicability of acoustic microscopy for fingerprint reading. The additional information from internal skin layers and dermis structures contained in the scan can essentially improve confidence in the identification. Advantages of this system include high resolution and quick scanning time. Operating in pulse-echo mode provides spatial resolution up to 0.05 mm. Technology advantages of the proposed technology are the following: • Full-range scanning of the fingerprint area "nail to nail” (2.5 x 2.5 cm) can be done in less than 5 sec with a resolution of up to 1000 dpi. • Collection of information about the in-depth structure of the fingerprint realized by the set of spherically focused 50 MHz acoustic lens provide the resolution ~ 0.05 mm or better • In addition to fingerprints, this technology can identify sweat porous at the surface and under the skin • No sensitivity to the contamination of the finger's surface • Detection of blood velocity using Doppler effect can be implemented to distinguish living specimens • Utilization as polygraph device • Simple connectivity to fingerprint databases obtained with other techniques • The digitally interpolated images can then be enhanced allowing for greater resolution • Method can be applied to fingernails and underlying tissues, providing more information • A laboratory prototype of the biometrics system based on these described principles was designed, built and tested. It is the first step toward a practical implementation of this technique.
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