We have devised and implemented a novel method for calculating the high dimensional field relating the brain surfaces (cortex) of an arbitrary pair of subjects. This non-rigid registration method uses crest lines as anatomical landmarks and various geometrical techniques such as geodesic voronoi diagram, barycentric flattening and barycentric coordinates to partition the cortex into meaningful regions and achieve a spatially accurate matching. Finally, the multilevel B-splines method is used to compute a C2 continuous warping field.
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