We present a fibre optic biosensor for SARS-CoV-2 detection based on the lossy-mode-resonance (LMR) [6] effect, generated in a single-mode fibre with a thinned cladding and coated by thin-film dielectric with appropriately selected optical properties and thickness. The detection of selected viral structural proteins in the tested sample is ensured by specific bioreceptors. As a result of the interaction with the SARS-CoV-2 antigen, optical response in the short-wave-IR range is observed, and the detection limit does not exceed 1.3*10^2 copies/ml, when converted to the viral load concentration - sufficiently for virus detection even in the first days after infection.
Anti-resonant hollow-core silica fiber is used to demonstrate near- and mid-infrared laser absorption spectroscopy of methane. Molecular transitions near 6057 cm-1 (~1651 nm) and at 3057.7 cm-1 (~3270 nm) are targeted. Distributed feedback laser diode and interband cascade lasers are used as tunable laser sources. Detection of methane in ambient air is demonstrated using this mid-infrared system.
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